Results 151 to 160 of about 251,089 (308)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

“ADMINISTRATIVE PROCEDURE” AS A BASIC CATEGORY FOR DEFINING THE ESSENCE OF ADMINISTRATIVE PROCEDURE LAW

open access: yesScientific notes of Taurida National V.I. Vernadsky University. Series: Juridical Sciences, 2021
V.K. Kolpakov   +2 more
openaire   +2 more sources

Nationwide Trends in Hospital-Acquired Pressure Ulcers, 2018-2024. [PDF]

open access: yesHealthcare (Basel)
Sebastiani E   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

RELATIONSHIPS BETWEEN GENERAL AND SPECIAL ADMINISTRATIVE PROCEDURES

open access: yes, 2017
Splošni upravni postopek je en sam, medtem ko poznamo nekaj sto posebnih upravnih postopkov. V Sloveniji so upravni postopki opredeljeni z Zakonom o splošnem upravnem postopku in s posebnimi specialnimi procesnimi pravili področne zakonodaje, ki urejajo ...
Javoršek, Špela
core  

Development efficiency and mortality after coronary artery bypass grafting: a national causal inference analysis. [PDF]

open access: yesJ Cardiothorac Surg
Martins GK   +6 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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