Results 181 to 190 of about 1,115,524 (338)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Road expansion risk predicts future hotspots of tropical deforestation. [PDF]

Proc Natl Acad Sci U S A
Engert JE, Souza CM, Kleinschroth F, Ishida FY, Costa SP, Botelho J, Laurance WF.   +6 more
europepmc   +1 more source

PREREQUISITES FOR THE OPENING OF CASSATION PROCEEDINGS IN THE ADMINISTRATIVE PROCESS OF UKRAINE

, 2022
K.V. Stafiichuk
openalex   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Comparison of Guarantees for the Implementation of the Principle of Competitiveness in Civil and Administrative Proceedings

, 2022
E. S. Smagina
openalex   +2 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

The New Path Forward for Prior Authorizations: Navigating Differences in the Accepted Standards of Care, Society Guidelines, and FDA-approved Indications. [PDF]

Open Forum Infect Dis
Desai AN, Rauseo A, Rogan GN, Spec A, Thompson GR.   +4 more
europepmc   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Integrated Health, Social, and Legal Approaches to Supporting Migrant Women Victims of Human Trafficking and Sexual Violence. [PDF]

Healthcare (Basel)
Jiménez-Lasserrotte MDM, El Marbouhe El Faqyr K, Escot MKEA, Rodas Vanegas MJ, Granero-Molina J, Hernández-Padilla JM.   +5 more
europepmc   +1 more source

ADMINISTRATIVE AND JURISDICTIONAL PROCEEDINGS IN ADMINISTRATIVE PROCEDURE

Juridical scientific and electronic journal, 2023
openaire   +1 more source