Results 121 to 130 of about 6,990 (302)

Administrative and legal liability for violations of environmental requirements in the cement industry

Теорія і практика інтелектуальної власності
The article studies administrative liability for infringements of environmental requirements in the cement industry of Ukraine as a tool for ensuring environmental safety.
Yuriy Korneyev
doaj   +1 more source

Administrative Sanctions in the European

, 2015
Book review of Administrative Sanctions in the European Union by Oswald Jansen (ed.)
openaire   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Enforcement of judgements in disputes over legality; study of practical case

Zbornik Radova Pravnog Fakulteta u Splitu, 2015
Although it is one of the fundamental characteristics of a state ruled by law, true and complete enforcement of administrative judgements which nullify certain administration acts has not always been guaranteed in France.
Jean-Michel Lemoyne de Forges
doaj  

Incomplete Sanctions for the Non-Procedural Transfer of Non-Public Village Treasury Land

Yurisdiksi: Jurnal Wacana Hukum dan Sains
This study aims to analyze the regulatory gap concerning sanctions in the transfer of village treasury land for non-public purposes that are not conducted in accordance with procedures under Minister of Home Affairs Regulation No.
Adinda Salma Rachmantya, Hamidi Masykur, Supriyadi   +2 more
doaj   +1 more source

The general sanction administrative procedure in Colombia

, 2019
El legislador con la expedición de la ley 1437 de 2011 estableció el procedimiento administrativo sancionatorio general, a fin de regular integralmente las diferentes actuaciones de la Administración que, en sus procedimientos especiales carezcan de ...
Sierra Avellaneda, Mónica
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The fane for breach dates of payment in external economic activity as a form of administrative and economic sanction

, 2010
В статье рассмотрена пеня за нарушение сроков расчетов во внешнеэкономической деятельности как вид административно-хозяйственной санкции и пути решения проблемных вопросов ее применения.In the article was examined the fane for breach dates of payment in ...
Глібко, С.В.
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source