Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
PADI-Location-AR-EN: A normalized Arabic-English spatial entity dataset for epidemiological surveillance. [PDF]
El Houbri FE +3 more
europepmc +1 more source
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Hospitalizations associated with endemic and non-endemic mosquito-borne arboviruses in Canada, 2002-2023. [PDF]
Mitri ME +6 more
europepmc +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Dataset of project-level records for the Special Development Program for Local Authorities "Antonis Tritsis" (approvals up to August 2025), Greece. [PDF]
Makryvelios E, Papadogonas T.
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Reassessing the emergency department burden of influenza: A comprehensive real-world analysis using administrative data. [PDF]
Khezrimotlagh D, Imanpour S, Akbas E.
europepmc +1 more source
The PULSE Vision & Change Rubrics,version 1.0: A valid and equitable tool to measure transformation of life sciences departments at all institution types [PDF]
et al,, Miller, Kathryn G
core +1 more source

