Results 201 to 210 of about 49,132 (303)

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

open access: yesAdvanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo   +14 more
wiley   +1 more source

Role of ethics, meritocracy, and professionalism in public sector reforms: A Q methodology study. [PDF]

open access: yesPLoS One
Abdul Kader Jilani MM   +4 more
europepmc   +1 more source

Tailoring K+ Dosage in K+/Zn2+ Mixed Electrolytes via Lattice Expansion Regulation of Zinc Hexacyanoferrate for High‐performance Zinc Ion Batteries

open access: yesAdvanced Science, EarlyView.
The study proposes a fitting curve as a reference to quantify the optimal K+ ratio in K+/Zn2+ mixed electrolyte, thus achieving stable and high‐capacity aqueous zinc ion batteries at each current density. ABSTRACT Incorporating K+ into Zn‐based electrolytes can enhance the performance of aqueous zinc ion batteries, while the lack of a clear rule for ...
Yewei Li   +7 more
wiley   +1 more source

Synergistic Stabilization of Potassium Metal Anodes Through Orange‐Peel Elimination and Robust Solid–Electrolyte Interphase Formation

open access: yesAdvanced Science, EarlyView.
Synergistic control of surface uniformity and solid–electrolyte interphase robustness regulates potassium deposition, suppressing dendritic growth and enabling uniform, dense potassium plating. This combined strategy promotes stable interfacial chemistry and homogeneous electric‐field distribution, leading to enhanced reversibility and long‐term ...
Pan He   +13 more
wiley   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

open access: yesAdvanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang   +15 more
wiley   +1 more source

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