Results 251 to 260 of about 186,998 (336)

Intracellular Aβ42 Sequestration by a Serine Protease Mitigates Neurotoxicity in a Drosophila Alzheimer's Disease Model

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Emerging evidence suggests that intraneuronal Aβ accumulation represents an early pathogenic event in Alzheimer's disease (AD). Using Drosophila AD model, this study shows that a nonsecreted serine protease Yip7 physically interacts with Aβ. This causes intraneuronal Aβ accumulation but surprisingly reduces the associated neurotoxicity, arguing that ...
Jingyun Su, Meng Yang, Xinfeng Wang, Pa Wu, Zongzhao Zhai   +4 more
wiley   +1 more source

Balancing mechanical-thermal-electrical properties in cellulose ionogels via crystallization-induced molecular assembly. [PDF]

Nat Commun
Li X, Tong Z, Qiu Y, Zheng Z, Zeng S, Zhao D, Yu H.   +6 more
europepmc   +1 more source

MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity

Advanced Science, Volume 13, Issue 26, 8 May 2026.
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen, Paili Lin, Yongfang Xia, Zhiqiang Liu, Zilu Cheng, Qingmei Zhu, Shiqi Wan, Xiaoyu Chen, Haiyan Bao, Renbo Qiao, Gechang Zhong, Ying Zhu, Shi Liu   +12 more
wiley   +1 more source

Evaluating the efficacy of eggshell-derived hydroxyapatite (EHA) and synthetic hydroxyapatite (SHA) in bone regeneration of maxillofacial defects-a randomized double-blind pilot comparative clinical-radiological study. [PDF]

J Oral Biol Craniofac Res
Changani K, Managutti A, Menat S, Patel N, Kattimani V, Panchal D, Girija EK.   +6 more
europepmc   +1 more source

Deciphering the Evolution Pattern of Structural Variations Overlapped With Repetitive Sequence During Cattle Evolution

Advanced Science, Volume 13, Issue 28, 18 May 2026.
The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo, Jinxiu Li, Adeniyi C. Adeola, Xueyan Jiang, Juntao Ma, Jian Xiao, Dexiang Hu, Kaixing Qu, Haihong Wu, Junren Chen, Zhanxing He, Tingting Yin, Ali Esmailizadeh, Jing Luo, Olivier Hanotte, Ya‐Ping Zhang, Yan Li   +16 more
wiley   +1 more source

Morphological Description and Physiological Changes in the Hindgut of Female Asiophrida xanthospilota (Chrysomelidae, Coleoptera) Across Reproductive Stages. [PDF]

Insects
Muinde JM, Dong ZQ, Ochieng CA, Wang W, Kioko EN, Zong L, Li WJ, Li CQ, Liu SP, Huang ZZ, Ge SQ.   +10 more
europepmc   +1 more source

CSGM: A R Package to Conduct a Robust Cross‐Sectional Geometric Morphometric Analysis

American Journal of Biological Anthropology, Volume 190, Issue 1, May 2026.
ABSTRACT Objective Evaluating the relationships between the shape and biomechanical function of bone cross‐sections can contribute novel insights towards human functional and evolutionary morphology. However, this research involves unique analytical and statistical challenges when comparing complex and multidimensional shape data to multivariate ...
Brian A. Keeling, Alessandro Urciuoli, Mercedes Conde‐Valverde, Julia Diez‐Valero, Laure Spake, Rolf Quam   +5 more
wiley   +1 more source

Deceptive beauty of non-natural structures. [PDF]

Protein Sci
Gurevich VV, Gurevich EV.
europepmc   +1 more source

Bildhintergrund entfernen mit Adobe Photoshop

Thomas Amstätter
openalex   +1 more source