Results 261 to 270 of about 186,998 (336)

Age‐related behavioral and molecular landmarks in new mouse models for studying Alzheimer's disease in Down syndrome

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Down syndrome (DS) is the leading genetic cause of intellectual disability and Alzheimer's disease (AD), with over 90% of individuals developing AD‐related dementia (DSAD). The triplication of the APP gene on chromosome 21 drives early amyloid‐β (Aβ) accumulation, but other Hsa21 genes also contribute to pathology.
Monika Rataj Baniowska   +18 more
wiley   +1 more source

Hominoid‐specific calretinin‐immunopositivity of the optic radiation (geniculocalcarine tract)

open access: yesThe Anatomical Record, Volume 309, Issue 5, Page 1343-1367, May 2026.
Calretinin‐immunostained coronal section through the primary (V1) and extrastriate (ExSt) cortex of the lar gibbon. Note that the optic radiation (OR) is strongly calretinin‐immunoreactive. This calretinin‐immunopositivity of the OR distinguishes the Hominoidea from other primates in terms of the neurochemistry of the OR.
Nelyane N. M. Santana   +5 more
wiley   +1 more source

Introducing functional dysplasia: Dynamic pelvic mechanics during running reduce femoral head coverage. [PDF]

open access: yesJ Exp Orthop
Locks R   +8 more
europepmc   +1 more source

RELB Overexpression Induced by DNA Hypomethylation Contributes to Perioperative Immunotherapy Resistance in Resectable Esophageal Squamous Cell Carcinoma by Modulating the mregDC‐Treg Axis

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
In patients with resectable ESCC, DNA hypomethylation driven RELB overexpression promotes resistance to perioperative immunotherapy (neoadjuvant ICIs followed by surgery and adjuvant ICIs). High RELB expression correlates with increased infiltration of mature immunoregulatory dendritic cells (mregDCs) and regulatory T cells (Tregs) in the tumor ...
Lijuan Gao, Shaobo Ke
wiley   +1 more source

Virtual Reality or Laptops? A Comparison of Two Formats for Developing Visualization Tools for Environmental Planning and Management

open access: yesComputer Animation and Virtual Worlds, Volume 37, Issue 3, May/June 2026.
A comparative evaluation of computer‐based and virtual reality visualization tools in environmental planning demonstrates that VR provides stronger experiential qualities, while both tools effectively communicate information, improve understanding of complex issues, and support informed decision‐making in watershed planning.
Bin Xu, Robert Newell, Brian White
wiley   +1 more source

Subtle differences in spring soil moisture can substantially influence annual productivity in a semiarid grassland

open access: yesEcosphere, Volume 17, Issue 5, May 2026.
Abstract In the C4‐dominated semiarid grasslands of the western Great Plains (Colorado, USA), spring soil moisture (soil volumetric water content, SoilVWC) is thought to be a critical determinant of aboveground net primary production (ANPP) and overall carbon cycling. However, because evidence for this is based on observational studies, we attempted to
Kathleen V. Condon, Alan K. Knapp
wiley   +1 more source

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