Results 41 to 50 of about 9,010 (258)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Trends and risk factors for physical and psychological sequelae of induced abortion: a cross-sectional study of contemporary women in the Republic of Korea [PDF]
Objectives This study aimed to examine trends and factors associated with severe physical and psychological consequences following induced abortion among women in the Republic of Korea.
Seung-Ah Choe +3 more
doaj +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Características neuropsicológicas en adolescentes infractores de la ciudad de Sincelejo-Sucre
Se da a conocer en este artículo, los resultados de una investigación que tuvo como objetivo caracterizar las alteraciones neuropsicológicas en adolescentes infractores institucionalizados en un programa del Sistema de Responsabilidad Penal para ...
Andres Fernando Ramirez Giraldo +1 more
doaj +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
School-based adolescent health survey in Himachal Pradesh, India: study design and protocol
BackgroundThe World Health Organization defined adolescent age group as a life span between 10 and 19 years. Adolescence is a phase of transition from childhood to adulthood, it is a unique stage for human development and a very sensitive period for ...
Saroj Mohanty +8 more
doaj +1 more source
[Resilience in institutionalized children and adolescents].
The concept of resilience refers to the possibility of individuals to develop positively when exposed to situations of adversity or stress. This is a complex process involving the interaction of vulnerability and protection factors. Researching resilience only makes sense when applied to populations considered at risk which, simultaneously, present ...
Catarina, Cordovil +3 more
openaire +1 more source
Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source

