Results 111 to 120 of about 1,870,691 (292)
Broadening Girls' Horizons: Effects of Life Skills Education Programme in Rural Uttar Pradesh [PDF]
, 2009 This report is the result of a collaborative project undertaken by Prerana and the Population Council to implement a life skills education programme for unmarried adolescent girls in rural Uttar Pradesh and to evaluate its effectiveness. The intervention
Rajib Acharya +3 more
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Advanced Science, EarlyView.Tumor‐derived extracellular vesicles program inflammatory lung premetastatic niches through selective delivery of long noncoding RNAs. This work reveals EVs‐associated lncOSLMT as a key driver of lung fibroblast activation via m6A‐dependent PTGS2 stabilization.
Hongbo Li +10 more
wiley +1 more source
Premarital Sex Among Adolescent Street Children in Pekanbaru [PDF]
, 2018 Premarital sex is any behavior that is driven by sexual desire with the opposite sex before marriage. Some premarital sex activities include feeling, kissing, necking, petting, and intercourse.
Alamsyah, A. (Agus) +2 more
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Advanced Science, EarlyView.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Srpski arhiv za celokupno lekarstvo, 2006 INTRODUCTION. Growth, development, and adaptation to numerous internal changes, as well as the changing roles of adolescents within the family and the community often take place within an environment of drug abuse, increased sexual freedom, weakened family structure, and under the strong influence of the media.
openaire +2 more sources
, 2011 Consultant child and adolescent psychiatrist Dr Sebastian Kraemer challenges assumptions and prejudices about ...
Kraemer, Sebastian
core
Advanced Science, EarlyView.Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo +7 more
wiley +1 more source
The Parent Attitudes about Childhood Vaccination against COVID-19 in Tunisia
European PsychiatryIntroduction The vaccination of children and adolescents against covid 19 is an ongoing debate. While in some countries the program of vaccination of children under 12 years old is already implemented, in others the balance of risk and benefits is a ...
I. Bouguerra +4 more
doaj +1 more source
Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
Advanced Science, EarlyView.The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source