Results 231 to 240 of about 1,870,691 (292)

Single‐Cell RNA Sequencing Informs Precision Targeting of Monogenic Lupus Associated With IKZF1 Haploinsufficiency

Arthritis &Rheumatology, EarlyView.
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng, Yejun Tan, Zhaoling Wang, Yanjie Qian, Qian Ma, Danping Shen, Meiping Lu   +6 more
wiley   +1 more source

Barriers and opportunities in implementing adolescent sexual and reproductive health interventions in rural Guatemala: an exploratory descriptive study. [PDF]

Rev Panam Salud Publica
Chaparro Buitrago DC, Baumann A, Wahoush O, Gombay C, O'Shea T.   +4 more
europepmc   +1 more source

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

Arthritis &Rheumatology, EarlyView.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

School-Based Weekly Iron-Folic Acid Supplementation and Its Effect on Mental Health Outcomes Among Adolescent Girls in Central Ethiopia: A Cluster-Randomized Controlled Trial. [PDF]

J Nutr Metab
Kedir S, Tamiru D, Ademe BW, Abate KH.
europepmc   +1 more source

Why We Need to Study Assisted Methods to Teach Typing to Nonspeaking Autistic People

Autism Research, EarlyView.
ABSTRACT At least one third of autistic people have limited or no speech. Most nonspeaking autistic people are never provided alternatives that would enable the full range of expression that speech allows, significantly limiting their access to educational, social, and employment opportunities.
Vikram K. Jaswal, Barry M. Prizant, Morgan D. Barense, Kristie Patten, Gary Stobbe   +4 more
wiley   +1 more source

Classification of knowledge of fertility period among adolescent girls in East Africa from 2012 to 2022: Machine learning algorithm. [PDF]

PLOS Digit Health
Birlie AA, Gashu KD, Kasaye MD, Muluneh AA, Kassaw AK, Desalegn HK, Desta TW, Kebede SD.   +7 more
europepmc   +1 more source

Changes in Intrinsic Activity of the Primary Somatosensory Cortex Causally Explain Differences in Emotion Perception in Autism

Autism Research, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is characterized by certain difficulties in emotion‐related processing. Recent research using electroencephalography (EEG) to measure somatosensory evoked potentials during emotion perception has shown reduced embodiment of emotional expressions in autistic compared to neurotypical individuals, independently from
Martina Fanghella, Danai Dima, Dimitrios Pinotsis, Sebastian B. Gaigg, Beatriz Calvo‐Merino, Bettina Forster   +5 more
wiley   +1 more source

Adverse birth outcomes and associated factors among adolescent mothers in Nabdam District, Ghana: a retrospective cross-sectional study. [PDF]

BMJ Open
Nborah SA, Saah FI, Gyamera OG, Amu H.
europepmc   +1 more source

Conversational Topic Shifts and Topic Maintenance in Autistic and Neurotypical Children

Autism Research, EarlyView.
ABSTRACT Topic maintenance and topic shifts are crucial components of conversation; however, existing research lacks a clear quantitative operationalization of these topic management skills. Previous studies suggest that autistic children are less likely than their neurotypical peers to maintain and elaborate on the interlocutor's prior topic, and that
Zuriñe Ábalos, Mikhail Kissine, Agustín Vicente, Elena Castroviejo   +3 more
wiley   +1 more source

Curiosity, coercion and coping: psychosocial drivers of youth drug use in Sri Lanka. [PDF]

BMJ Paediatr Open
Dayasiri K, Samarasinghe M, Gawarammana I.   +2 more
europepmc   +1 more source