Results 231 to 240 of about 600,648 (272)

Comparative Analysis of Phenotypic and Genotypic Differences Between Individuals Affected by Regressive and Non‐Regressive Autism: A Cross‐Sectional Study

Autism Research, EarlyView.
ABSTRACT Development among autistic youth varies widely. A subgroup of children experiences regression, defined as the loss of previously acquired developmental skills. Various genetic and environmental factors have been suggested as potential contributors.
Seyed Hassan Tonekaboni, Alana Iaboni, Brett Trost, Miriam Reuter, Zsuzsa Lindenmaier, Azadeh Kushki, Elizabeth Kelley, Jessica Jones, Muhammed Ayub, Stelios Georgiades, Robert Nicolson, Elim Chan, Andrada Cretu, Jessica Brian, Evdokia Anagnostou   +14 more
wiley   +1 more source

Cognitive and Cerebral Aging Research in Autism: A Systematic Review on an Emerging Topic

Autism Research, EarlyView.
ABSTRACT Aging in autism is an emerging and under‐explored area of research. This systematic review provides a comprehensive overview of studies on cognitive and both structural and functional cerebral aging in autism. A systematic search of PubMed and APA PsycInfo was conducted up to and including January 2024.
Marine Bessé, Shasha Morel‐Kohlmeyer, Emmanuelle Houy‐Durand, Philippe Prévost, Laurie Tuller, Badiâa Bouazzaoui, Laurence Taconnat, Julia Capdeville, Lucie Angel, Marie Gomot   +9 more
wiley   +1 more source

Linguistic and Musical Syntax Processing in Autistic and Non‐Autistic Individuals: An Event‐Related Potential (ERP) Study

Autism Research, EarlyView.
ABSTRACT Syntactic processing in both language and music involves combining elements—such as words or chords—into coherent structures. The Shared Syntactic Integration Resource Hypothesis (SSIRH) was introduced based on observations of similar neural responses to syntactic violations across both domains.
Jiayin Li, Anna Petrova, Zivile Bernotaite, Maleeha Sujawal, Chen Zhao, Hiba Ahmed, Cunmei Jiang, Fang Liu   +7 more
wiley   +1 more source

Multisensory Integration of Naturalistic Speech and Gestures in Autistic Adults

Autism Research, EarlyView.
ABSTRACT Seeing the speaker often facilitates auditory speech comprehension through audio‐visual integration. This audio‐visual facilitation is stronger under challenging listening conditions, such as in real‐life social environments. Autism has been associated with atypicalities in integrating audio‐visual information, potentially underlying social ...
Magdalena Matyjek, Sotaro Kita, Mireia Torralba Cuello, Salvador Soto Faraco   +3 more
wiley   +1 more source

Population pharmacokinetics and dosing of dispersible moxifloxacin formulation in children with rifampicin‐resistant tuberculosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Moxifloxacin is a priority drug for treating rifampicin‐resistant tuberculosis (RR‐TB). We assessed the pharmacokinetics of a child‐friendly, dispersible 100 mg tablet moxifloxacin formulation (dispersed in water) compared to the standard 400 mg non‐dispersible formulation (crushed and suspended in water) in children and evaluated current dosing ...
Megan Palmer, Yuanxi Zou, Anneke C. Hesseling, Louvina van der Laan, Ingrid Courtney, Aarti A. Kinikar, Naresh Sonkawade, Mandar Paradkar, Vandana Kulkarni, Dessa Jean O. Casalme, Melchor V. G. Frias, Heather Draper, Lubbe Wiesner, Mats O. Karlsson, Paolo Denti, Elin M. Svensson, Anthony J. Garcia‐Prats   +16 more
wiley   +1 more source

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao, Marie Mostue Naume, Brenda C. M. de Winter, Thomas Krag, Sissel Sundell Haslund‐Krog, Karoline Lolk Revsbech, John Vissing, Helle Holst, Morten Hylander Møller, Tessa Munkeboe Hornsyld, Morten Dunø, Christina Engel Hoei‐Hansen, Alfred Peter Born, Per Bo Jensen, Mette Cathrine Ørngreen   +14 more
wiley   +1 more source

Epilepsy and the Adolescent

Journal of the Royal College of Physicians of London, 2000
openaire   +3 more sources

Analysis of 4616 clinical trial initial submissions received by the Medicines and Healthcare products Regulatory Agency between February 2019 and October 2023

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse clinical trial initial submissions received by the MHRA between February 2019 and October 2023. Methods Data on submissions were extracted from the clinical trials unit data bank. The primary end‐point was the type of clinical trial initial submissions.
Andrea Manfrin, Kingyin Lee, James Pound, Munir Pirmohamed, June Raine   +4 more
wiley   +1 more source

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The Hospitalized Adolescent

Pediatrics, 2023
This policy statement is the first published statement in the United States on this topic and the authors aim to provide pediatricians with evidence-based information on the unique aspects required to care for hospitalized adolescents. Included in this policy statement is a description of the possible effects hospitalization may have on the ...
Cora C. Breuner, Elizabeth M. Alderman, Jennifer A. Jewell, Cora C. Breuner, Elizabeth M. Alderman, Jennifer Jewell, Elise Berlan, Richard J. Chung, Michael Colburn, Laura K. Grubb, Janet Lee, Stephenie B. Wallace, Makia Powers, Krishna K. Upadhya, Anne-Marie Amies, Liwei L. Hua, Ellie Vyver, Seema Menon, Lauren B. Zapata, Maria Rahmandar, Karen Smith, James Baumberger, Daniel A. Rauch, Samantha House, Benson Hsu, Melissa Mauro-Small, Nerian Ortiz-Mato, Charles Vinocur, Nicole Webb, Kimberly Ernst, Vinh Lam, Michael S. Leonard, Karen Castleberry, Nancy Hanson, Kristin Hittle Gigli, Barbara Romito, S. Niccole Alexander   +36 more
openaire   +3 more sources

Adolescences physiologiques, adolescences pathologiques

Bulletin de l'Académie Nationale de Médecine, 2006
The uncertainties of looming adulthood, nostalgia for childhood, and a general malaise explain the crisis of adolescence. Rebellion, conflict, occasional failure at school or in society, and at-risk behaviors are not always signs of future psychiatric illness.
Olivier Canceil, David Gourion, Henri Lôo, Jean-Pierre Olié   +3 more
openaire   +3 more sources