Results 81 to 90 of about 600,648 (272)

Immunity Debt for Seasonal Influenza After the COVID‐19 Pandemic and as a Result of Nonpharmaceutical Interventions: An Ecological Analysis and Cohort Study

Advanced Science, EarlyView.
This study provides support for the immunity debt hypothesis, revealing a 131.72% increase in influenza rates during winter and a 161.23% rise in summer, 1 year following the global easing of COVID‐19 restrictions. This study offers empirical evidence of immunity debt on a global level, highlighting the importance of incorporating this concept into the
Li Chen, Yuchen Guo, Kim López‐Güell, Jun Ma, Yanhui Dong, Junqing Xie, Daniel Prieto Alhambra   +6 more
wiley   +1 more source

ACOMPANYA’M a novel multimodal intervention plan

European Psychiatry
Introduction The Residential Educational Therapeutic Unit Accompany from Hospital Sant Joan de Déu Barcelona, is a device integrated into the public health network, intended for the comprehensive care of children and adolescents under 18 years of age ...
I. Insa Pineda, I. Rueda Bárcena, C. Lamborena Ramos, F. de Pedro Melgarejo, A. Planas Bas, T. Prieto Toribio, E. Lujan Lujan, M. Ribas Siñol   +7 more
doaj   +1 more source

Wrist-bound Guanxi, Jiazu, and Kuolie: Unpacking Chinese Adolescent Smartwatch-Mediated Socialization [PDF]

Adolescent peer relationships, essential for their development, are increasingly mediated by digital technologies. As this trend continues, wearable devices, especially smartwatches tailored for adolescents, are reshaping their socialization. In China, smartwatches like XTC have gained wide popularity, introducing unique features such as "Bump-to ...
arxiv   +1 more source

scHeteroNet: A Heterophily‐Aware Graph Neural Network for Accurate Cell Type Annotation and Novel Cell Detection

Advanced Science, EarlyView.
scHeteroNet) is a novel graph neural network model that explicitly addresses heterophily in single‐cell sequencing data enabling accurate cell type annotation and novel cell type discovery. By leveraging heterophily‐aware message passing and novelty propagation mechanisms, scHeteroNet achieves superior performance in both cell annotation and detection ...
Jiacheng Liu, Xingyu Fan, Chunbin Gu, Yaodong Yang, Bian Wu, Guangyong Chen, Chang‐Yu Hsieh, Pheng‐Ann Heng   +7 more
wiley   +1 more source

Looking into the crystal ball: quality of life, delinquency, and problems experienced by young male adults after discharge from a secure residential care setting in the Netherlands

Child and Adolescent Psychiatry and Mental Health, 2019
Background Adolescents in residential care are a vulnerable population with many problems in several life areas. For most of these adolescents, these problems persist after discharge and into adulthood.
E. A. W. Janssen-de Ruijter, E. A. Mulder, I. L. Bongers, L. Omlo, Ch. van Nieuwenhuizen   +4 more
doaj   +1 more source

Improving Adult Vision Through Pathway‐Specific Training in Augmented Reality

Advanced Science, EarlyView.
Traditional perceptual training approaches are limited by stimulus specificity, treatment efficacy, and patient compliance. A novel altered reality (AR) method is developed to enhance pathway‐specific functions in human adults while performing everyday activities.
Yige Gao, Yulian Zhou, Qing He, Wen Wen, Peng Zhang   +4 more
wiley   +1 more source

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

Implants in adolescents

Journal of Indian Society of Periodontology, 2013
Implants have gained tremendous popularity as a treatment modality for replacement of missing teeth in adults. There is extensive research present on the use of implants in adults, but there is a dearth of data available on the same in adolescents. The treatment planning and execution of implant placement in adolescents is still in its infancy.
Rohit Shah, Dipika Mitra, Pragalbha N Pathare, Harshad Vijayakar, Silvia Rodrigues, Rajesh S Podar   +5 more
openaire   +3 more sources

Paternal Obesity‐Induced H3K27me3 Elevation Leads to MANF‐Mediated Transgenerational Metabolic Dysfunction in Female Offspring

Advanced Science, EarlyView.
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi, Weisheng Li, Xi Yu, Yan Zhao, Dan Zhu, Yueyang Song, Zejun Zhao, Yannan Gu, Bin Wei, Lingjun Li, Dongyi Yu, Pengjie Zhang, Qinqin Gao, Miao Sun   +13 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source