Results 81 to 90 of about 1,180,187 (301)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Conflict resolution in adolescent relationships [PDF]

, 2008
Conflict is an inevitable feature of social relationships. When people interact, disagreements may arise. Especially in close relationships, people sometimes disagree.
van Doorn, M.D., LS Meeus, Dep Educatie & Pedagogiek, Adolescent development: Characteristics and determinants   +3 more
core   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source

Bridging the marrow: a co-culture-platform of leukemia cells and MS5-derived stromal cells or adipocytes

Cell Death Discovery
In the context of acute lymphoblastic leukemia (ALL), the bone marrow microenvironment (BMM) plays a crucial role in providing pro-survival signals, as evident from the rapid spontaneous cell death observed in ex-vivo cultures of primary ALL cells. Among
Julia Zinngrebe, Elena Dorothea Brenner, Ferdinand Schlichtig, Ulrich Stifel, Daniel Tews, Jana Falk, Dominik Schlotter, Rahel Fitzel, Lüder-Hinrich Meyer, Klaus-Michael Debatin, Pamela Fischer-Posovszky   +10 more
doaj   +1 more source

Does your mother know? : parent-child communication about adolescent daily activities [PDF]

, 2010
Juvenile offending is a wide-spread problem in Western societies: More than half of the adolescents engage in minor forms of delinquency, and this causes high material and immaterial costs.
Dep Educatie & Pedagogiek, Leerstoel Meeus, Keijsers, L., Adolescent development: Characteristics and determinants   +3 more
core   +1 more source

Generalized Dystonia With Cervical Predominance in a Patient With a De Novo TCF20 Variant

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT TCF20 has been implicated in developmental delay and intellectual disability, with dystonia reported less frequently. We describe a woman in her early twenties with childhood‐onset learning difficulties, progressive dysarthria, tremor, and generalized dystonia with marked cervical predominance, associated with a de novo TCF20 frameshift ...
Melisa Kilic, Petr Dusek, Ibrahim Kamaci, Bahar Gulmez, Gul Yalcin Cakmakli, Ersin Tan, Sibel Ugur Iseri, Zuhal Yapici   +7 more
wiley   +1 more source

Independent contribution of emotion dysregulation to suicide attempts in adolescents beyond the role of depressive symptoms

Scientific Reports
Emotion dysregulation (ED) is increasingly recognized as a transdiagnostic factor in adolescent psychopathology and suicidal ideation and behavior. This study examined the association between ED and recent suicide attempts (SAs) in a clinically referred ...
Massimo Apicella, Maria Pontillo, Gino Maglio, Alessandra Minutolo, Giulia Serra, Giorgia Della Santa, Elisa Andracchio, Giulia D’Amario, Milena Labonia, Roberto Averna, Stefano Vicari   +10 more
doaj   +1 more source

Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez, Amy Tam, Siofra Carty, Monica Ferrer Socorro, Kathryn Yang, Darius Ebrahimi‐Fakhari   +5 more
wiley   +1 more source

Presence of a trusted adult and adolescent health outcomes in Urban India

Discover Public Health
Background Adolescents in urban India face significant challenges in accessing healthcare and reliable health information, particularly during crises such as the COVID-19 pandemic.
Anupam Sharma, Priya Shankar, Ricky Sharma, Nelabh Krishna, Nanditha Jayakumar, Samruddhi Nalawade, Avani Doshi, Aruna Nannapaneni, Vandana Krishnan, Mohammed Danish, Kym Ahrens, Sarah Golub, Rajib Dasgupta, Latha Ravichandran, Padma Srikanth, Sarala Premkumar, Jason M. Nagata, Vaishali Keswani, Isabel Allen, Julia Seaman, Harish Pemde   +20 more
doaj   +1 more source