Results 131 to 140 of about 851,969 (312)

The Association Between Parental Phubbing and Preschoolers’ Excessive Electronic Media Use: The Chain Mediating Role of Parent–Child Attachment and Self-Control

Behavioral Sciences
In the current digital age, children are exposed to electronic media at an increasingly early age. The issue of excessive electronic media use has become a significant risk factor affecting the healthy development of young children.
Qiong Zhao, Yanrong Fan, Kuai Song, Zhengyi Wang, Zongkui Zhou   +4 more
doaj   +1 more source

Sluggish Cognitive Tempo among Iranian Children and Adolescents: A Validation Study of the Farsi Child and Adolescent Behavior Inventory (CABI)-Parent Version. [PDF]

J Clin Med, 2022
Sadeghi-Bahmani D, Mohammadian Y, Ghasemi M, Bahmani LS, Piri N, Brühl AB, Becker SP, Burns GL, Brand S.   +8 more
europepmc   +1 more source

Effective Interventions for Treating Superficial Self Mutilators [PDF]

, 2008
Self-cutting is the most common form of self-mutilation in adolescents but there is insufficient knowledge as to which treatment methods to reduce self-mutilation are most effective.
Palladini, Maria
core   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Mediators of the Relation of Family Income with Adolescent Behavior Problems and Cognitive Achievement: Material Hardship, Parent Distress and Parent Support. [PDF]

Infant Child Dev, 2022
Near CE.
europepmc   +1 more source

First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria

Advanced Science, EarlyView.
We report the first PROTACs designed to degrade progerin, introducing a novel therapeutic approach for progeria. The best compound, UCM‐18142, significantly reduces progerin levels and improves key disease phenotypes in patient‐derived cells and in the LmnaG609G/G609G mouse model, paving the way for new treatment strategies targeting the root cause of ...
Jon Macicior‐Michelena, Marcelino Telechea, Daniel Fernández, Alba García‐Martín, Ángeles Canales, Silvia Ortega‐Gutiérrez   +5 more
wiley   +1 more source

Therapist Self-Report of Fidelity to Core Elements of Family Therapy for Adolescent Behavior Problems: Psychometrics of a Pragmatic Quality Indicator Tool. [PDF]

Adm Policy Ment Health, 2022
Hogue A, Bobek M, Porter N, MacLean A, Bruynesteyn L, Jensen-Doss A, Henderson CE.   +6 more
europepmc   +1 more source

The Impact of Abstinence-Only Sex Education Programs in the United States on Adolescent Sexual Outcomes [PDF]

, 2019
Though there are many evaluations of abstinence-only sex education programs in the United States, there is a relatively small body of literature exploring the programs’ impact specifically on adolescent sexual behavior.
Heels, Sonja W.
core   +2 more sources

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

Psychometric and Normative Information on the Child and Adolescent Behavior Inventory in a Nationally Representative Sample of United States Children. [PDF]

J Clin Child Adolesc Psychol, 2022
Burns GL, Preszler J, Becker SP.
europepmc   +1 more source