Results 81 to 90 of about 871,114 (289)

HOPE Kids 2: Phase 3, Randomized Trial of Voxelotor in Children With SCD and Conditional Cerebral Blood Flow Velocities

American Journal of Hematology, EarlyView.
ABSTRACT Children with SCD have elevated stroke risk, correlated with cerebral blood flow velocity (CBFV). HOPE Kids 2 was a phase 3, multicenter, double‐blind, placebo‐controlled trial evaluating the effect of voxelotor on CBFV. Participants aged 2 to < 15 years with SCD (HbSS/HbSβ0) and conditional CBFV (170 to < 200 cm/s) were randomized 1:1 to ...
Halima Bello‐Manga, Shehu Umar Abdullahi, Hoda Hassab, Biobele Brown, Videlis Nduba, Jessie Githanga, Adeseye Michael Akinsete, Amal El‐Beshlawy, Diana Hanna, Catherine Segbefia, Iheanyi Okpala, Azza Tantawy, Bernhards Ogutu, Venée N. Tubman, Vivian Paintsil, Yasser Wali, Mohammed Essa, Paul Telfer, Sandy Dixon, Anne Hickman, Jennifer F. Doss, Mark W. Davis, Jeremy Rupon, Fenella J. Kirkham, R. Clark Brown, on behalf of the HOPE Kids 2 Investigators, Amal El‐Beshlawy, Mohamed Badr, Diana Hanna*, Hoda Hassab, Azza Tantawy, Vivian Paintsil, Catherine Segbefia, Raffaella Colombatti, Daniela Cuzzubbo, Silverio Perrotta, Jessie Githanga, Videlis Nduba, Bernhards Ogutu, Shehu Umar Abdullahi, Adeseye Michael Akinsete, Halima Bello‐Manga, Biobele Brown, Iheanyi Okpala, Yasser Wali, Mohammed Essa, Banu Kaya, Paul Telfer, Ofelia Alvarez, Natasha Archer, Shayla Bergmann, R Clark Brown, Andrew Campbell, Carlton Dampier*, Richard Hurwitz, Erin Jackson, Janet Kwiatkowski, Melissa M. McNaull*, Venée N. Tubman   +58 more
wiley   +1 more source

Donor Roundtable—Sustaining Progress: Investing in adolescent girls amidst global challenges

The Coalition for Adolescent Girls (CAG) in collaboration with Akili Dada convened a virtual donor roundtable on Sustaining Progress: Investing in adolescent girls amidst global challenges, on June 4, 2025. The purpose of the roundtable was to assess the
Coalition for Adolescent Girls
core   +1 more source

Vulval haemangioma in an adolescent girl

Journal of Obstetrics and Gynaecology, 2011
A 13-year-old girl presented with a 1-month history of vulval swellings, gradually getting bigger and causing discomfort. She attained menarche at the age of 12 and her periods since were regular.
C, Madhu, M A, Khaled, J, Putran
openaire   +2 more sources

Navigating Asparaginase Treatment for Patients With Acute Lymphoblastic Leukemia: US Consensus Panel Recommendations on the Role of Multidisciplinary Care

American Journal of Hematology, EarlyView.
ABSTRACT Asparaginase is a critical treatment component for patients with acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL). However, the successful delivery of asparaginase‐based therapy remains challenging across care settings due to its complex administration, distinct toxicity profile, prolonged treatment duration, and the need for ...
Amir Ali, Grace Elsey, Kayla Fulginiti, Zanette Kanani‐Bradley, Holly R. Kubaney, Sandra Kurtin, Theresa Nguyen, Jennifer Turchina, Charlotte B. Wagner   +8 more
wiley   +1 more source

Forced displacement, household composition, and mental health: how gendered family structures relate to adolescent girls’ well-being

BMC Public Health
Background Venezuelan migrants in South America are at heightened risk for mental distress due to factors such as discrimination, unstable employment, and gender-based violence (GBV).
Lindsay Stark, Arturo Harker Roa, Carolina Rodriguez, Elvia Tamaity Ariza Pena, Julianne Deitch, Ilana Seff   +5 more
doaj   +1 more source

Influence Factors of Reproductive Organ Maintenance Among Adolescent Girls in Coastal Areas

Jurnal Kesehatan
Adolescent girls are vulnerable to reproductive health problems such as vaginal discharge and reproductive tract infections, which are triggered by poor maintenance of their reproductive organs.
Armyla Eka Wahyu Yuliani, Lu'lu Nafisah, Bambang Hariyadi   +2 more
doaj   +1 more source

What Are the Barriers Which Discourage 15-16 Year-Old Girls from Participating in Team Sports and How Can We Overcome Them? [PDF]

, 2013
Given the clear benefits of regular physical activity (such as reduced risks of cardiovascular disease and obesity, as well as other benefits including those related to mental health), exploration of the reasons that adolescent girls give for not taking ...
Radley, Rebecca, Pearce, Mark, Wetton, Abigail, Jones, Angela   +3 more
core   +1 more source

Passing as “Normal”: Adolescent Girls’ Strategies for Escaping Stigma of Premarital Sex and Childbearing in Ghana

SAGE Open, 2018
Premarital sex and premarital childbearing is a source of stigma in many African communities and can negatively affect adolescent girls’ sexual and reproductive health experiences.
Sylvia Esther Gyan
doaj   +1 more source

Federal Protections for Farmworker Health in the United States: A Scoping Review of Three Decades of Research

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Objectives This scoping review characterizes the scope, methods, and framing of empirical research evaluating the Field Sanitation Standard (FSS) and Worker Protection Standard (WPS) of the U.S. Environmental Protection Agency and the U.S. Department of Labor respectively.
Kaitlyn Alvarez Noli, Stephane Labossiere, Becca Berkey, Joseph G. Grzywacz   +3 more
wiley   +1 more source

Ocular and Systemic Findings in COL2A1 and COL11A1 Stickler Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Stickler syndrome is most commonly caused by variants in COL2A1 and COL11A1 genes. The purpose of this study was to describe genetic variants and phenotypes in COL2A1 and COL11A1 Stickler syndrome. We performed a retrospective genotype–phenotype evaluation of COL2A1 and COL11A1 Stickler syndrome subjects. Thirty‐two subjects with COL2A1 and 13
Aileen G. MacLachlan, Jessica A. Kraker, Denise J. Morgan, Lisa A. Schimmenti, M. Elizabeth Hartnett, Eileen S. Hwang   +5 more
wiley   +1 more source