Results 61 to 70 of about 9,927 (176)

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, Volume 13, Issue 53, 24 September 2026.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source

Reliability of Sensorimotor Control Tests in Individuals with Adolescent Idiopathic Scoliosis

Muscles
Background: The presence of sensorimotor control deficits in adolescent idiopathic scoliosis compared to typically developed adolescents is supported by the literature but lacks reliability studies for assessment in this population.
Alexandros Kastrinis, Nikolaos Strimpakos, George A. Koumantakis, Dionysios Tzatzaliaris, Marianna Oikonomaki, Evangelos Theodosopoulos, Evangelia Skaftourou, Maria Tsekoura, Asimakis K. Kanellopoulos, Eleni Nomikou, Zacharias Dimitriadis   +10 more
doaj   +1 more source

Adolescent idiopathic scoliosis in adulthood

EFORT Open Reviews
Adolescent idiopathic scoliosis (AIS) is an abnormal coronal curvature of the spine that most commonly presents in adolescence. While it may be asymptomatic, AIS can cause pain, cosmetic deformity, and physical and ...
Kashif Ansari, Manjot Singh, Jake R McDermott, Jerzy A Gregorczyk, Mariah Balmaceno-Criss, Mohammad Daher, Christopher L McDonald, Bassel G Diebo, Alan H Daniels   +8 more
openaire   +2 more sources

The Oral Microbiome of King Richard III of England

American Journal of Biological Anthropology, Volume 191, Issue 1, September 2026.
ABSTRACT Objectives Metagenomic investigations of ancient dental calculus provide insights into oral health, disease, and diet. Here, we analyze the dental calculus metagenome of King Richard III of England (1452–1485). Materials and Methods Dental calculus DNA was extracted from three teeth of King Richard III and shotgun sequenced to a depth of ...
Irina M. Velsko, Alexander Hübner, Zandra Fagernäs, James A. Fellows Yates, Allison E. Mann, Courtney A. Hofman, Andrew T. Ozga, Cecil M. Lewis Jr., Camilla Speller, Sarah Fiddyment, Michael Francken, Joachim Wahl, Johannes Krause, Anita Radini, Turi King, Christina Warinner   +15 more
wiley   +1 more source

Hidden blood loss in adolescent idiopathic scoliosis patients undergoing posterior spinal fusion surgery: a retrospective study of 765 cases at a single centre

BMC Musculoskeletal Disorders, 2021
Background In scoliosis corrective surgery, total blood loss is composed of visible blood loss, including intraoperative haemorrhage and drainage, and hidden blood loss in which blood extravasates into the tissues and accumulates in the surgical field ...
Lipeng Wang, Jiangli Liu, Xiaoxiao Song, Muhui Luo, Yongquan Chen   +4 more
doaj   +1 more source

Evaluation of Curve Flexibility Using Scoliotic Spines Generated From a Generic Spine Model

International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 9, September 2026.
This study presents a modelling procedure to evaluate curve flexibility in adolescent idiopathic scoliosis. Models were generated from a previously assessed adolescent spine model, with patient radiographs used to estimate traction forces. Sequential spinal release simulations were conducted.
Yifan Su, Athanasios I. Tsirikos, Vasileios Koutsos, Pankaj Pankaj   +3 more
wiley   +1 more source

Galectin‐4: A Novel Mediator of Human Intervertebral Disc Degeneration

JOR SPINE, Volume 9, Issue 3, September 2026.
Galectin‐4 correlates with intervertebral disc degeneration, independent of age, sex, or underlying pathology. Functionally, it activates NF‐κB signaling and induces pro‐inflammatory and matrix‐degrading responses, with stronger effects in nucleus pulposus cells, identifying it as a novel molecular player in disc degeneration.
Christine Strauss, Daniel Djojic, Johannes Stadlmann, Josef Georg Grohs, Jürgen Alphonsus, Sebastian Schmidt, Sabine André, Katharina Margareta Pichler, Sara Savic‐Ivanovic, Melanie Cezanne, Mario Rothbauer, Reinhard Windhager, Stefan Toegel   +12 more
wiley   +1 more source

ADOLESCENT IDIOPATHIC SCOLIOSIS

Journal of Pediatric Orthopaedics, 1988
Adolescent idiopathic scoliosis is the single most common form of spinal deformity seen in orthopedic practice. Our knowledge about the epidemiology, etiology, natural history, and treatment has recently increased dramatically. The incidence of small curves is rather high (2% of the population), whereas severe curves are much less common (
L A, Rinsky, J G, Gamble
openaire   +3 more sources

Idiopathic scoliosis: Etiological concepts and hypotheses

Journal of Children's Orthopaedics, 2013
Scoliosis is diagnosed as idiopathic in 70 % of structural deformities affecting the spine in children and adolescents, probably reflecting our current misunderstanding of this disease.
Romain Dayer, Thierry Haumont, Wilson Belaieff, Pierre Lascombes   +3 more
doaj   +1 more source

Growth Plate Morphogens as Potential Modulators of Cellular Tissue Remodeling by Annulus Fibrosus Cells

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background Adolescent Idiopathic Scoliosis (AIS) is a spinal deformity of unknown etiology that begins in the intervertebral disc and emerges during pubertal growth. In the vertebral growth plate, adjacent to the disc, powerful growth plate morphogens (GPMs) modulate this growth. We evaluated whether GPMs can also alter the capacity of annulus
K. Stradovnik‐Poikilidis, M. Teunissen, F. M. Riemers, M. van Doeselaar, J. Foolen, F. Abinzano, M. A. Tryfonidou, S. J. P. Callens, K. Ito   +8 more
wiley   +1 more source