Results 341 to 350 of about 2,185,996 (384)

Urban physical disorder and alcohol consumption among adolescents in Brazilian capitals: a cross-sectional study. [PDF]

Cad Saude Publica
Dias RM, Lopes CS, Cortes TR, Bloch KV, Junger WL.   +4 more
europepmc   +1 more source

Characterizing local and systemic exposure to clobetasol propionate in healthy subjects and patients with atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims There is a potential risk of systemic side‐effects with the use of potent corticosteroids, such as clobetasol propionate (CP). This concern is of particular interest in paediatric patients. The aim of this study was to develop and verify a physiologically based pharmacokinetic (PBPK) model to describe the local and systemic exposure to CP
Janna K. Duong, Sven van Dijkman, Gary Ong, Alexandra Marta, Adriana Ceci, Ernesto Bonifazi, Oscar Della Pasqua   +6 more
wiley   +1 more source

HIV prevention among adolescents travestis and transgender women in three Brazilian capitals, 2019-2023. [PDF]

Epidemiol Serv Saude
Leite BO, Magno L, Greco D, Grangeiro A, Dourado I.   +4 more
europepmc   +1 more source

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

Erratum. [PDF]

Rev Saude Publica
europepmc   +1 more source

Effects of rapid maxillary expansion on auditory thresholds and middle ear functioning. [PDF]

Codas
Moraes CF, Gomes E, Helena RCS, Sleifer P.   +3 more
europepmc   +1 more source

External validation of a therapeutic window for risperidone in children with autism spectrum disorder

British Journal of Clinical Pharmacology, EarlyView.
Abstract Although risperidone is an effective pharmacological intervention for managing disruptive behaviour in children with autism spectrum disorder, it may induce metabolic side effects. This study aimed to externally validate the population pharmacokinetic (popPK) model and the therapeutic window of 3.5–7 ng/mL of risperidone and 9‐OH‐risperidone ...
Rebecca A. Hermans, Kathalijne Bruens, Karin M. Egberts, Birgit C. P. Koch, Bram Dierckx, Manon H. J. Hillegers, Marcel Romanos, Regina Taurines, Stefanie Fekete, Khatia Eisenecker, Hans‐Willi Clement, Christian Fleischhaker, Brenda C. M. de Winter   +12 more
wiley   +1 more source

Adolescents and parents experiencing parental cancer: construction of a nursing intervention model. [PDF]

Rev Esc Enferm USP
Sousa AFD, Sousa PCMM, Ferreira MMDSRDS, Lomba MLLF.   +3 more
europepmc   +1 more source

Real‐world population pharmacokinetics of tezacaftor‐ivacaftor in children with cystic fibrosis: The SYM‐CF study

British Journal of Clinical Pharmacology, EarlyView.
Aims The clinical effectiveness of tezacaftor‐ivacaftor in children with cystic fibrosis (cwCF) varies; some patients respond while others do not or have adverse effects. The pharmacokinetics (PK) of tezacaftor‐ivacaftor are inadequately published, especially in children.
Steffie E. M. Vonk, Suzanne W. J. Terheggen‐Lagro, Eric G. Haarman, Hettie M. Janssens, Anke‐Hilse Maitland–van der Zee, E. Marleen Kemper, Ron A. A. Mathôt, on behalf of the Amsterdam Mucociliary Clearance Disease (AMCD) research group   +7 more
wiley   +1 more source