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Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang+16 more
wiley +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu+5 more
wiley +1 more source
Auto-observación en adolescentes: los problemas de la escala de auto-observación de Snyder en poblaciones no adultas [PDF]
Los objetivos de la presente investigación fueron examinar las diferencias en la variable de personalidad auto -observación (AO) entre adolescentes y jóvenes adultos, y extender la investigación sobre su validez de constructo a la población de ...
Graña Gómez, José Luís+1 more
core +1 more source
Activation of HTR2B suppresses osteosarcoma progression through the STAT1‐NLRP3 inflammasome pathway and promotes OASL1+ Macrophage production to enhance anti‐tumor immunity. Abstract Osteosarcoma is a primary malignant bone tumor originating from mesenchymal tissue, and associated with poor prognosis.
Zhen Huang+7 more
wiley +1 more source
The role of personality and social support in the development of internalizing psychopathology and well-being in adolescents [PDF]
Treball Final de Grau en Psicologia. Codi: PS1048. Curs: 2018/2019.Adolescence is a period of transition and maturation between childhood and adult life, in which physical, psychological and social changes occur.
Sahuquillo Sahuquillo, Raquel
core
New research reveals that oxytocin signaling during the early postnatal period is critical for regulating brain development and social behavior. Selectively suppressing oxytocin neurons by chemogenetic method shows that early—but not late—disruption leads to autism‐like behaviors.
Zi‐Hui Wang+10 more
wiley +1 more source
Rastreio de escoliose no adolescente [PDF]
No artigo «Boletim de Saúde Infantil e Juvenil - o exame global de saúde dos 11 aos 13 anos (parte II)»,1 é referida a importância da realização do rastreio de escoliose no exame global de saúde dos 11 aos 13 anos, através da realização, entre outros, da manobra de Adams.
openaire +4 more sources
Improving Adult Vision Through Pathway‐Specific Training in Augmented Reality
Traditional perceptual training approaches are limited by stimulus specificity, treatment efficacy, and patient compliance. A novel altered reality (AR) method is developed to enhance pathway‐specific functions in human adults while performing everyday activities.
Yige Gao+4 more
wiley +1 more source
Survey of children accessing HIV services in a high prevalence setting: time for adolescents to count? [PDF]
OBJECTIVE: To establish the proportion of adolescents among children infected with human immunodeficiency virus (HIV) in Zimbabwe who receive HIV care and support, and what clinic staff perceives to be the main problems faced by HIV-infected children and
Arpadi+34 more
core +2 more sources