Results 71 to 80 of about 1,340,927 (354)

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Crisis epilepticas en la población infantil

Revista Médica Clínica Las Condes, 2011
Las crisis epilépticas son un problema neurológico que afecta entre un 4-10% de los niños hasta los 16 años. Las crisis deben ser diferenciadas de otros desórdenes neurológicos de los niños y clasificadas según su tipo.
B. Francesca Solari
doaj   +1 more source

Cooperación al desarrollo y formación universitaria

Comillas Journal of International Relations, 2020
Los programas de Educación para el Desarrollo en el ámbito universitario responden a la responsabilidad que tienen las universidades de contribuir a dar respuesta a los desafíos la Agenda 2030 de Naciones Unidas de lucha contra la pobreza y la ...
Belén Pascual Barrio, Maria Antònia Gomila Grau, Rosario Pozo Gordaliza, Carlos Vecina Merchante, Gabriela Rentería Hernández   +4 more
doaj   +1 more source

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Mujeres adolescentes y privación de libertad en la provincia de Santa Fe, Argentina. Un análisis 'situado' sobre género y desigualdad en el campo de los sistemas penales juveniles (Adolescent women and deprivation of liberty ...)

Sortuz, 2020
El presente artículo propone aportar algunos elementos de reflexión sobre los abordajes planteados desde el sistema penal juvenil argentino con las mujeres adolescentes infractoras privadas de la libertad.
Laura Mónica Oliva Gerstner
doaj  

Clinical Use of S53P4 Bioactive Glass in the Treatment of Bone Defects and Infected Bone: A Systematic Review of the Quality of Clinical Outcomes and A Grade Assessment

Advanced Healthcare Materials, EarlyView.
Bioactive glass (BAG) S53P4 is a synthetic bone substitute. Clinically it has been used in the treatment of benign bone tumor surgery, in spine surgery, in trauma surgery, in frontal sinus surgery, in diabetic foot osteomyelitis surgery, in mastoid surgery, in oral and maxillofacial surgery in more than 4000 patients, with excellent clinical long‐term ...
Lindfors CES, Arts JJC, Lindfors NC
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

A INFLUÊNCIA DE FATORES SOCIODEMOGRÁFICOS NA EXPRESSÃO DE COMPORTAMENTOS AUTOLESIVOS NÃO SUICIDÁRIOS (NSSI) EM ADOLESCENTES PORTUGUESES [PDF]

, 2017
A manifestação de comportamentos autolesivos não suicidários (NSSI) tem vindo a aumentar entre os adolescentes. Pretende-se com esta investigação identificar a frequência e os tipos de autodano praticados por adolescentes portugueses e analisar a ...
Barreira, Alexandra, Castilho, Paula, Nobre-Lima, Luiza   +2 more
core  

¿Nativos digitales? Percepción de habilidades en niños y niñas de zonas rurales

Cuadernos de Investigación Educativa, 2023
Los niños de zonas rurales se han enfrentado históricamente a severas desventajas tanto en el ámbito educativo como en el digital. La pandemia de COVID-19 ha sido un recordatorio de las barreras que deben sortear debido a la inestable señal de internet,
Isabel Pavez
doaj  

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source