Results 141 to 150 of about 2,598,782 (346)

Family, teachers and peer support as predictors of school engagement among secondary school Ethiopian adolescent students

, 2022
Ejigu Olana, Belay Tefera
openalex   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Virtual Reality-Based Alcohol Prevention: The Results of a Cross-Sectional Study with Visitors of an Art Exhibition

Adolescents
Virtual reality (VR) can help to prevent alcohol consumption by simulating peer pressure. While existing VR applications for adolescents are primarily tested in schools, expanding them to museums and art galleries offers setting-specific benefits and ...
Robert Hrynyschyn, Sergej Kucenko, Patricia Bianca Lyk, Gunver Majgaard, Susanne Rockweiler, Sara Stehr, Christiane Stock   +6 more
doaj   +1 more source

Adolescents [PDF]

Journal of Paediatrics and Child Health, 2013
openaire   +2 more sources

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Genetic, Neurobiological, and Social Determinants of Adolescent Behavior: Risk Pathways and Protective Mechanisms

Adolescents
Adolescence is a critical period, marked by heightened risk-taking and experimentation, which are significantly influenced by the interactions between genetic predisposition and environmental contexts [...]
Paola Carbone
doaj   +1 more source

“Pharmacies are Everywhere, and You can get it at any Time”: Experiences With Pharmacy-Based PrEP Delivery Among Adolescent Girls and Young Women in Kisumu, Kenya

, 2023
Melissa Vera, Elizabeth A. Bukusi, Pauline Achieng, Helen Aketch, Evelyne Araka, Jared M. Baeten, Kristin Beima‐Sofie, Grace John‐Stewart, Pamela Kohler, Melissa Latigo Mugambi, Bernard Nyerere, Josephine Odoyo, Caroline Omom, Christine Omondi, Katrina F. Ortblad, Jillian Pintye   +15 more
openalex   +1 more source

Adolescent smoking [PDF]

Canadian Medical Association Journal, 2007
C Jairaj, Kumar, Arunachalam, Kumar
openaire   +2 more sources

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

The Impact of Internet Addiction on Mental Health: Exploring the Mediating Effects of Positive Psychological Capital in University Students

Adolescents
Introduction: The widespread use of the internet has brought numerous benefits, but it has also raised concerns about its potential negative impact on mental health, particularly among university students.
Girum Tareke Zewude, Derib Gosim Bereded, Endris Abera, Goche Tegegne, Solomon Goraw, Tesfaye Segon   +5 more
doaj   +1 more source