We applied quantitative MRI of the lower limb and automated home‐cage phenotyping to a mouse model of calpainopathy to detect early disease changes. At 15 months, calpain 3‐deficient mice showed increased water T2 values correlating with immune cell infiltration in the soleus and gastrocnemius muscles, while assessment of motor activity revealed only ...
Nicolina Südkamp +12 more
wiley +1 more source
Trends in e-cigarette use among adolescents in Malaysia, 2016-2022: A secondary dataset analysis of national surveys. [PDF]
Mohd Yusoff MF +4 more
europepmc +1 more source
Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral +52 more
wiley +1 more source
Prevalence of sexual and reproductive health issues among school-going adolescents in Hulu Langat District, Malaysia: Findings from the Borang Saringan Status Kesihatan Remaja - A cross-sectional study. [PDF]
Maryem SF +4 more
europepmc +1 more source
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose +2 more
wiley +1 more source
Exploring Mental Health Barriers Among At-Risk Adolescents: An Integrative Analysis of Self-Reports and School Nurses' Perspectives. [PDF]
Kim M, Baek S.
europepmc +1 more source
Abstract The human mandibular symphysis concentrates multiaxial loads during function and remodels throughout growth, but the precise mechanisms underlying cortical bone shape during growth remain relatively unexplored. Approaches based solely on thickness or external cortical contours provide only partial insights and do not capture the functional ...
Ana Ribeiro +3 more
wiley +1 more source
Body Appreciation and Weight Control Behaviors in Overweight Adolescents: A Cross-Sectional Study Informing a CBT-Based Health Promotion Model. [PDF]
Wu X, Xu Q, Wu Z, Zheng L.
europepmc +1 more source
Integrating whole‐bone and regional analyses to understand human scapular growth
Abstract This study investigates ontogenetic changes in human scapular morphology using three‐dimensional geometric morphometrics with whole‐bone and region‐specific analyses. The aim is to evaluate whether the scapula follows a regular developmental pattern and whether its functionally distinct components, the scapular spine (SS) and glenoid fossa ...
Azahara Salazar‐Fernández +3 more
wiley +1 more source
Audience Interpretation of Risks in Health Promotion Campaigns About Underage Drinking: Qualitative Interviews With Parents of Adolescents. [PDF]
Nguyen HV.
europepmc +1 more source

