Results 61 to 70 of about 2,501,354 (348)

Psychological functioning in adolescents referred to specialist gender identity clinics across Europe : a clinical comparison study between four clinics [PDF]

, 2017
Adolescents seeking professional help with their gender identity development often present with psychological difficulties. Existing literature on psychological functioning of gender diverse young people is limited and mostly bound to national chart ...
Ball, Juliane, Carmichael, Polly, Cohen-Kettenis, Peggy T, de Graaf, Nastasja M, de Vries, Annelou LC, Dhondt, Karlien, Laridaen, Jolien, Pauli, Dagmar, Steensma, Thomas D   +8 more
core   +3 more sources

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Sleep Disturbances and Fatigue in Adolescents with Cancer Receiving Chemotherapy [PDF]

, 2014
Sleep disturbances and fatigue are frequently complained by adolescents with cancer. These problems will lead to a variety of changes that may affect adolescents’ development.
Allenidekania, A. (Allenidekania), Rahmawaty, F. (Fetty), Waluyanti, F. T. (Fajar)   +2 more
core   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Sleep-amount differentially affects fear-processing neural circuitry in pediatric anxiety: A preliminary fMRI investigation. [PDF]

, 2017
Insufficient sleep, as well as the incidence of anxiety disorders, both peak during adolescence. While both conditions present perturbations in fear-processing-related neurocircuitry, it is unknown whether these neurofunctional alterations directly link ...
Carlisi, Christina O, Ernst, Monique, Guyer, Amanda E, Hilbert, Kevin   +3 more
core   +1 more source

Single‐Cell RNA Seq in Sydenham Chorea Shows B Cell HLA‐DR/DQ Upregulation and Plasma Cell Proteasomal Activation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han, Brooke A. Keating, Brian S. Gloss, Xianzhong Lau, Ruwani Dissanayake, Hiroya Nishida, Jessica Hayes, Shrujna Patel, Shekeeb S. Mohammad, Russell C. Dale   +9 more
wiley   +1 more source

Adolescents’ view and experiences of living with type 1 diabetes [PDF]

, 2016
This literature review aims to explore the perceptions and experiences of adolescents living with Type 1 Diabetes, and its impact on their lives. The prevalence and the number of adolescents living with this condition are rapidly increasing in western ...
Ellis, M.R.C., Jayarajah, C.
core   +1 more source

INF2‐Related Charcot–Marie–Tooth Disease in a Japanese Cohort: Genetic and Clinical Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background INF2 mutations cause focal segmental glomerulosclerosis (FSGS) and Charcot–Marie–Tooth disease (CMT). Accurate genetic diagnosis is critical, as INF2‐related FSGS is typically resistant to immunotherapy yet rarely recurs after transplantation, and its associated neuropathy can mimic treatable immune‐mediated disorders such as ...
Chikashi Yano, Masahiro Ando, Yujiro Higuchi, Jun‐Hui Yuan, Akiko Yoshimura, Takahiro Hobara, Risa Nagatomo, Fumikazu Kojima, Yu Hiramatsu, Satoshi Nozuma, Tomonori Nakamura, Yusuke Sakiyama, Chika Matsuoka, Toru Yamashita, Takashi Kimura, Ayako Miyazaki, Chinatsu Kinjo, Kenji Yokochi, Nanami Yamanaka, Nozomu Matsuda, Tomoki Suichi, Yoshiyuki Hanaoka, Haruka Kojima, Kenichi Todo, Hiroyuki Ishiura, Jun Mitsui, Shoji Tsuji, Hiroshi Takashima   +27 more
wiley   +1 more source

Perceived Parenting Styles and Psycho-social Wellbeing of Nigerian Adolescents [PDF]

, 2020
The influence of parenting styles on the psychosocial wellbeing of Nigerian adolescents is yet to be given adequate research attention. This study bridges the gap in knowledge.
Akinnawo, Ebernezer O.
core  

Reliability and validity of three questionnaires measuring context-specific sedentary behaviour and associated correlates in adolescents, adults and older adults [PDF]

, 2015
BACKGROUND: Reliable and valid measures of total sedentary time, context-specific sedentary behaviour (SB) and its potential correlates are useful for the development of future interventions.
AE Cust, AJ Atkin, AJ Viera, AS Singh, AS Singh, B Wallmann-Sperlich, BE Saelens, BK Clark, C Wang, CA Vereecken, CE Matthews, Cedric Busschaert, D Jacobi, D Macfarlane, DE Rosenberg, EB Hekler, FC Bull, GJ Norman, GM Dwyer, GN Healy, Greet Cardon, H Spittaels, H Spittaels, HJ Helmerhorst, I Ajzen, Ilse De Bourdeaudhuij, J Barnes, J Cauwenberg Van, J Cohen, J Lefevre, JM Bland, JR Ruiz, K Wijndaele, Katrien De Cocker, KP Dowd, L Uijtdewilligen, LFM Rezende de, LFM Rezende de, LL Hardy, LL Hardy, M Hagstromer, M Hamer, M Visser, MJ Chinapaw, MJ Duncan, N Owen, O Affuso, PA Gardiner, PM Grant, RE Rhodes, RG McMurray, S Kozey-Keadle, S Kozey-Keadle, S Scholes, Sebastien FM Chastin, SF Chastin, SF Chastin, SF Chastin, SF Chastin, SFM Chastin, V Rangul, Veerle Van Holle, Y Liu, YJ Huang   +63 more
core   +6 more sources