Results 121 to 130 of about 1,549,649 (314)
Accreditation of ICA mediation agencies : draft guidelines
, 2003 The objective of the report is to present draft guidelines for the accreditation and registration by the Irish Adoption Board (Now Adoption Authority of Ireland) of intercountry adoption mediation agencies that are based in Ireland.
O'Brien, Valerie
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Corporate Plan 2012 - 2015 [PDF]
, 2014 The Adoption Authority has examined how the staff and organisational structure is suited to its functions and the legislative environment. An early objective of the Corporate Plan is to implement decisions regarding organisational structure and ...
Adoption Authority of Ireland
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Report of the Adoption Board 1985
, 1985 During the year, 882 adoption orders were made. Since the Adoption Act, 1952, came into operation on 1st January, 1953, a total of 33,817 adoption orders have been made up to 31st December, 1985.For the third year in succession there was a reduction in
Adoption Board
core
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Report of the Adoption Board 1997
, 1998 This is the final Report of the present Board whose term of office finishes on the 29th January, 1998. The Board received 108 applications for domestic adoption orders in respect of children placed by Registered Adoption Societies and Health Boards in ...
Adoption Board
core
, 2002 In this article several justifications of what I call `the claim from adoption' are examined. The claim from adoption is that, instead of expending resources on bringing new children into the world using reproductive technology and then caring for those
Petersen, Thomas Sobirk
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source