Results 91 to 100 of about 86,483 (289)
FEBS Open Bio, EarlyView.Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar +11 more
wiley +1 more source
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
Intra-Firm Adoption Decisions [PDF]
The subject of this paper is intra-firm adoption decisions, a relatively unexplored research area in the marketing literature. In particular, we investigate which factors influence the intra-firm adoption decisions regarding the common European currency ...
Wierenga, B., Everdingen, Y.M. van
core
De-Adoption and Un-Diffusion [PDF]
Journal of the American College of Radiology, 2015 Gunderman, Richard B. +1 more
openaire +2 more sources
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
Zvi Griliches and the Economics of Technology Diffusion: Adoption of Innovations, Investment Lags, and Productivity Growth. [PDF]
The first version of this paper was presented to the Conference on R&D, Education and Productivity, held in Memory of Zvi Griliches (1930 –1999) on 25-27th, August 2003 at Carr? des Sciences, Ministère de la Recherche, Paris, France.
Paul A. David
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Digital BusinessDigital and telemedicine innovations are increasingly central to healthcare transformation, yet their adoption and diffusion remain complex. While the Diffusion of Innovations (DOI) theory explains staged adoption processes, it underrepresents socio ...
Yvonne Rauner, Harald Stummer
doaj +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Microeconomics of Technology Adoption [PDF]
There is an emerging consensus among macro-economists that differences in technology across countries accounts for the major differences in per-capita GDP and the wages of workers with similar skills across countries.
Mark R. Rosenzweig, Andrew D. Foster
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Modelling innovation adoption spreading in complex networks
Applied Network ScienceInnovation adoption pattern has been found to be influenced by the underlying social network structure and its constituent entities. In this paper, we model innovation diffusion considering (1) the role of network structures in dictating the spread of ...
Jing-Lin Duanmu, Wei Koong Chai
doaj +1 more source