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Adoptive T cell immunotherapy for cytomegalovirus
Expert Opinion on Biological Therapy, 2009Cytomegalovirus (CMV) is a major opportunistic pathogen following allogeneic transplantation, reflecting the inability of depressed host immunity to contain viral replication. Current antiviral drugs are limited by toxicities and lack of efficacy in established CMV disease, making adoptive immunotherapeutic strategies aimed at hastening virus-specific ...
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CASE FOR ADOPTIVE IMMUNOTHERAPY IN CANCER
The Lancet, 1982Patients with normal immune systems may be unable to mount effective defences against solid tumours because of (1) the generation of suppressor T cells in the low zone tolerance response elicited by the low concentrations of antigen furnished by slow growing solid tumours; (2) the ineffectiveness of the cytolytic T-cell response when the tumour cell ...
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Ordinary Differential Equation Models for Adoptive Immunotherapy
Bulletin of Mathematical Biology, 2018Anne M. Talkington +2 more
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The emerging roles of γδ T cells in cancer immunotherapy
Nature Reviews Clinical Oncology, 2023Sofia Mensurado +2 more
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Dynamics and specificities of T cells in cancer immunotherapy
Nature Reviews. Cancer, 2023G. Oliveira, Catherine J. Wu
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