Results 71 to 80 of about 167,858 (268)

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye   +8 more
wiley   +1 more source

ADR and Scottish commercial litigators : a study of attitudes and experience [PDF]

open access: yes, 2007
Reports on the findings of a study of the use of alternative dispute resolution (ADR) by commercial litigators in Scotland. Analyses survey responses from commercial litigators on a range of issues, including: (1) their own knowledge of, training in, and
Clark, Bryan, Dawson, Charles
core  

Clinical Study to Evaluate Drug Interactions of Cannabidiol with Citalopram and Morphine in Healthy Adults

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cannabidiol (CBD) is one of the most abundant bioactive cannabinoids. Research has demonstrated CBD’s ability to inhibit metabolic enzymes like cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT), potentially leading to drug interactions. However, clinical knowledge gaps remain, particularly with regard to drugs that are more commonly taken by ...
Pablo Salcedo   +11 more
wiley   +1 more source

SV2A expression in blood cells as a possible biomarker candidate for levetiracetam treatment response

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether synaptic vesicle protein 2A (SV2A) expression on peripheral immune cells predicts treatment response to levetiracetam in epilepsy. Methods High‐dimensional flow cytometry was used to prospectively assess SV2A expression on immune cells from levetiracetam responders, nonresponders, and ...
Johannes Lang   +4 more
wiley   +1 more source

Autophagy-deficient breast cancer shows early tumor recurrence and escape from dormancy [PDF]

open access: yes, 2018
Breast cancer patients who initially respond to cancer therapies often succumb to distant recurrence of the disease. It is not clear why people with the same type of breast cancer respond to treatments differently; some escape from dormancy and relapse ...
Manjili, Masoud H.
core   +1 more source

Fast ripple‐delta coupling as an early biomarker for post‐traumatic epileptogenesis in repetitive brain injury

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Traumatic brain injury (TBI) can induce posttraumatic epilepsy (PTE), but early biomarkers for epileptogenesis are lacking. We aimed to investigate electrographic biomarkers before and during posttraumatic seizure development. Methods We used a repetitive diffuse TBI model in mice with continuous video‐EEG monitoring up to 4½ months ...
Oleksii Shandra   +7 more
wiley   +1 more source

Equality of Arms in the Digital Age [PDF]

open access: yes, 2008
Electronic commerce is important, and perhaps, inevitable. Thus to consider the legal implications of the growth and development of electronic commerce is essential.
Haloush, Haitham   +2 more
core  

Health economic considerations for pharmacogenomic services in the United Kingdom: The Centre for Excellence in Regulatory Science and Innovation in Pharmacogenomics

open access: yes
British Journal of Clinical Pharmacology, EarlyView.
Dyfrig A. Hughes   +4 more
wiley   +1 more source

Catalyst Functionalization for Elevating Performance in Ammonia Protonic Ceramic Fuel Cells via Relay Thermo‐Electrocatalysis

open access: yesExploration, EarlyView.
Direct ammonia proton ceramic fuel cell (NH3‐PCFC) typically underperforms at intermediate temperatures due to slow ammonia decomposition at the anode. By applying a Ru/CZ4 catalytic layer, this study enhances ammonia decomposition, with NH3‐PCFC power density at 650°C reaching 93.7% of H2‐fueled PCFC, offering valuable insights into optimizing fuel ...
Huihuang Fang   +10 more
wiley   +1 more source

Recent changes in the pharmacovigilance system in the Russian Federation and the EAEU

open access: yesФармакоэкономика, 2019
The Eurasian Economic Union (EAEU) is an international organization for regional economic integration, established by the Treaty on the Eurasian Economic Union, which currently includes 5 countries - Russia, Kazakhstan, Belarus, Armenia and Kyrgyzstan ...
G. N. Gildeeva, A. V. Belostotsky
doaj   +1 more source

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