Results 321 to 330 of about 783,304 (397)

Pregnancy Outcomes in Women With Primary Adrenal Insufficiency: Data From a Multicentre Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 8, Page 1122-1129, July 2025.
ABSTRACT Objective To determine characteristics and pregnancy outcomes in women with primary adrenal insufficiency (PAI). Design Retrospective multicentre cohort study. Setting Twenty‐three maternity units in the UK and Ireland. Sample Seventy‐nine women with PAI who had 101 pregnancies. Method Retrospective chart analysis.
Matthew Cauldwell, Philip J. Steer, Masato Ahsan, Amanda Ali, Shabana Ashiq, Rebecca Ashworth, Deena Basha, Hsu Chong, Gillian A. Corbett, Fidelma Dunne, Amanda Hill, Katarzyna Gajewska‐Knapik, Adam Jakes, David McLaren, Therese Kinsella, Tara Lee, Miles Levy, Lucy MacKiliop, Fionnuala M. McAuliffe, Aarthi Mohan, Clare Mumby, Melanie Nana, Catherine Napier, Francesca Neuberger, Christine Newman, Tabitha Oosterhouse, Amelia Shard, Hassan Shehata, Linden Stocker, Jeremy W. Tomlinson, Adele Beck, Bijay Vaidya, Kate Wiles, Catherine Williamson, Julia Zollner, Emma Ward, Helen E. Turner   +36 more
wiley   +1 more source

Early positive tactile stimulation reverses the increase of anxiety and decrease of sociality induced by early chronic mechanical pain in mandarin voles

Integrative Zoology, Volume 20, Issue 4, Page 712-727, July 2025.
This study used a tail‐pinching model during development to simulate mechanical pain experienced by pups in high‐social mandarin voles (Microtus mandarinus). Subsequently, brush‐like positive tactile stimuli were applied to the backs of the mandarin voles.
Yahan SUN, Jiayu XIAO, Luoman LI, Haiwei NIU, Yiting ZHU, Lu LI, Wei QIAN, Yin LI, Lizi ZHANG, Yishan QU, Yuting BAI, Xiao HAN, Kaizhe HUANG, Zhixiong HE, Fadao TAI   +14 more
wiley   +1 more source

The Role of Oxytocin and Oxytocin Gene Receptor Methylation During Withdrawal Therapy in Males With Alcohol Use Disorder

Addiction Biology, Volume 30, Issue 7, July 2025.
This study investigates the effect of alcohol withdrawal therapy on promoter methylation of the oxytocin and oxytocin receptor gene. We found significantly higher mean methylation values of the receptor gene in controls compared with patients across withdrawal and no differences in mean methylation of the oxytocin gene.
Phileas J. Proskynitopoulos, Alissa F. Haarmeyer, Stefan Bleich, Helge Frieling, Thomas Hillemacher, Alexander Glahn, Mathias Rhein   +6 more
wiley   +1 more source

Tools to Predict Unilateral Primary Aldosteronism and Optimise Patient Selection for Adrenal Vein Sampling: A Systematic Review

Clinical Endocrinology, Volume 103, Issue 1, Page 3-12, July 2025.
ABSTRACT Objective Primary aldosteronism (PA), the most common endocrine cause of hypertension, is evaluated using adrenal vein sampling (AVS), to determine if aldosterone excess is bilateral or unilateral. AVS is invasive and technically challenging; it would ideally be used only in those with unilateral PA who are candidates for surgical cure.
Elisabeth Ng, Stella May Gwini, Winston Zheng, Peter J. Fuller, Jun Yang   +4 more
wiley   +1 more source

Oxytocin Intervention Mitigates Pathological and Behavioral Impairments in APP/PS1 Mice Subjected to Early Social Isolation

CNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.
Social isolation exacerbates anxiety, depression, and social cognitive deficits in early‐stage AD mice by disrupting the oxytocin system, while intranasal oxytocin mitigates behavioral abnormalities, reduces pathological damage, and restores gut microbiota homeostasis.
Junjun Li, Yue Li, Zhuoya Wang, Yuan Yao, Dezhong Yao, Ke Chen, Yang Xia   +6 more
wiley   +1 more source

Roles and Impacts of Integrative Medical Interventions in Central Nervous System Tumor Treatment: Multi‐Technology Convergence and the Paradigm Shift Toward Functional Reconstruction

CNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.
Multi‐technology interventions (non‐invasive neuromodulation, AI, 3D organoids) for CNS tumor treatment shift from monotherapy to functional reconstruction. They address BBB restriction, tumor heterogeneity, and immune suppression via biological–psychological–technological convergence, enabling precision oncology through dynamic monitoring and ...
Junda Lai, Ketao Liu, Yuhua Lin, Zhonglin Chen, Xianglun Ji, Junkai Wen   +5 more
wiley   +1 more source

Announcing the Biomedical Data Translator: Initial Public Release

Clinical and Translational Science, Volume 18, Issue 7, July 2025.
ABSTRACT The growing availability of biomedical data offers vast potential to improve human health, but the complexity and lack of integration of these datasets often limit their utility. To address this, the Biomedical Data Translator Consortium has developed an open‐source knowledge graph–based system—Translator—designed to integrate, harmonize, and ...
Karamarie Fecho, Gwênlyn Glusman, Sergio E. Baranzini, Chris Bizon, Matthew Brush, William Byrd, Lawrence Chung, Andrew Crouse, Eric Deutsch, Michel Dumontier, Aleksandra Foksinska, Jennifer Hadlock, Kaiwen He, Sui Huang, Robert Hubal, Gregory M. Hyde, Sharat Israni, Kelyne Kenmogne, David Koslicki, Jana Dorfman Marcette, Ewy A. Mathe, Abrar Mesbah, Sierra A. T. Moxon, Christopher J. Mungall, John Osborne, Carrie Pasfield, Guangrong Qin, Stephen A. Ramsey, Justin Reese, Jared C. Roach, Reese Rose, Karthik Soman, Andrew I. Su, Casey Ta, Gaurav Vaidya, Rosina Weber, Qi Wei, Mark Williams, Chunlei Wu, Colleen Xu, Chase Yakaboski, The Biomedical Data Translator Consortium, Michel Arab, Shervin Abdollahi, Nichollette Acosta, Ayushi Agrawal, Stanley Ahalt, Nada Amin, Michael Bada, Krish Balar, Jim Balhoff, William Baumgartner, Jon‐Michael Beasley, Emily Blake, Namdi Brandon, Richard Bruskiewich, Noel Burtt, Jackson Callaghan, Terese Camp, Marco Alvarado Cano, Kathleen Carter, Remzi Celebi, Cheng‐Han Chung, Larry Chung, Maria Costanzo, Margot Cousin, Tim Curry, Vlado Dancik, Jennifer Dougherty, Marc Duby, Stephen Edwards, Joe Farris, Nate Fehrmann, Marta Figueiral, Jason Flannick, Charlie Fox, Amy Glen, Prateek Goel, Skye Goetz, Joseph Gormley, Perry Haaland, Kristina Hanspers, Nomi Harris, Jeff Henrickson, Anthony Hickey, Eugene Hinderer, Maureen Hoatlin, Tursynay Issabekova, Rhea Karty, Yaphet Kebede, Keum Joo Kim, Simon King, Eric Klee, Michael R. Knowles, Ryan Koesterer, Daniel Korn, Ashok Krishnamurthy, Laura Lambert, Margaret W. Leigh, Jason Lin, Max Lupey, Chunyu Ma, Andrew Magis, Mallika Mainali, Meisha Mandal, Luis Mendoza, Matthew Might, Evan Morris, Kenny Morton, Sandrine Muller, Kamileh Narsinh, Olawumi Olasunkanmi, Deepak Panwar, Michael Patton, David B. Peden, Amber Peters, Alexander Pico, Filippo Pinto e Vairo, Nishad Prakash, Guthrie Price, Sundareswar Pullela, Anthony Ragazzi, Navya Ramakrishnan, Jason Reilly, Everaldo Rodolpho, Greg Rosenblatt, Irit Rubin, Rayn Sakaguchi, Eugene Santos, Ava Schaak, Johnathan Schaff, Kevin Schaper, Shepherd Schurman, Brett Smith, David Smith, Sarah Stemann, Michael Strasser, Harsha Sureshbabu, Mohsen Taheri, Alexander Tropsha, Sarah Tyndall, Adam Viola, Kevin Vizhalil, Madison Walker, Chen Wang, Max Wang, Braiden Wardon, Paul B. Watkins, Ximing Wen, Chunhua Weng, Elizabeth White, Stephanie Won, Erica Wood, Braiden Worden, Yao Xiao, Rena Yang, Hong Yi, Qian Zhu, Tom Zisk   +158 more
wiley   +1 more source