Results 51 to 60 of about 783,304 (397)
Familial Micronodular Adrenocortical Disease, Cushing Syndrome, and Mutations of the Gene Encoding Phosphodiesterase 11A4 ( PDE11A) [PDF]
, 2014 We present the pathologic findings in the adrenal glands of 4 patients, aged 10 to 38 years, with Cushing syndrome and germline inactivating mutations of the gene PDE11A4 that encodes phosphodiesterase11A4. The gene is expressed in the adrenal cortex and
Bertherat, J. +3 more
core +1 more source
Functional zonation of the rat adrenal cortex: the development and maintenance
Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2014 The adrenal cortex of mammals consists of three concentric zones, i.e., the zona glomerulosa (zG), the zona fasciculata (zF), and the zona reticularis (zR), which secrete mineralocorticoids, glucocorticoids, and adrenal androgens, respectively.
F. Mitani
semanticscholar +1 more source
Hypoadrenocorticism in an aged cat [PDF]
, 2018 A 13-year-old, female, neutered, domestic longhair cat was referred to the hospital with a two-month history of fluctuating weakness, lethargy, inappetence and intermittently soft stools.
Fowlie, Samuel J. +2 more
core +1 more source
Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury
Advanced Science, EarlyView.Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley +1 more source
Evaluating the role of aldosterone synthesis on adrenal cell fate
Frontiers in EndocrinologyHypertension affects one-third of the adult population worldwide, with primary aldosteronism (PA) accounting for at least 5-10% of these cases. The aldosterone synthase enzyme (CYP11B2) plays a pivotal role in PA manifestation, as increased expression of
Amnani Aminuddin +5 more
doaj +1 more source
Acta Médica Portuguesa, 1979 Mean plasma cortisol 4 to 6 hours after 1 mg Synacthen Depot in normal subjects, simple goiter and hypothyroidism were not significantly different. On the contrary after stimulation cortisol levels in untreated hyperthyroidism were significantly below ...
A. Galvão-Teles
doaj +1 more source
Latent Adrenal Insufficiency: From Concept to Diagnosis
Frontiers in Endocrinology, 2021 Primary adrenal insufficiency (PAI) is a rare disease and potentially fatal if unrecognized. It is characterized by destruction of the adrenal cortex, most frequently of autoimmune origin, resulting in glucocorticoid, mineralocorticoid, and adrenal ...
Nada Younes +2 more
doaj +1 more source
Brain Differences in the Prefrontal Cortex, Amygdala, and Hippocampus in Youth with Congenital Adrenal Hyperplasia [PDF]
, 2020 Context: Classical Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency results in hormone imbalances present both prenatally and postnatally that may impact the developing brain.
Azad, Anisa +5 more
core
Advanced Science, EarlyView.Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu +7 more
wiley +1 more source
Acta Pediátrica de México, 2014 Background: Adrenal cortex tumors (ACT) are extremely rare in children and adolescents. Only 0.2% of all the new cases of cancer diagnosed in the United Stated and Europe are adrenal cortex tumors.
Paola de Baro-Álvarez +4 more
doaj +1 more source