Results 61 to 70 of about 783,304 (397)

The Multifaceted Etiology of Mental Disorders With a Focus on Trace Elements, a Review of Recent Literature

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Mental disorders are a significant global public health concern, affecting nearly one in eight individuals worldwide. This review investigates the multifaceted etiology of mental disorders—specifically major depressive disorder (MDD), schizophrenia (SCZ), and bipolar disorder (BD)—through genetic, neurobiological, and environmental ...
Maria Francesca Astorino, Marco Calabrò, Carmenrita Infortuna, Maria Rosaria Anna Muscatello, Silvana Briuglia, Nicola Cicero, Chiara Fabbri, Alessandro Serretti, Concetta Crisafulli   +8 more
wiley   +1 more source

Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient.

PLoS ONE, 2015
BackgroundNeurofibromatosis type I (NF1, MIM#162200) is a relatively frequent genetic condition, which predisposes to tumor formation. Apart from tumors, individuals with NF1 often exhibit endocrine abnormalities such as precocious puberty (2,5-5% of NF1
Karolina Kobus, Daniela Hartl, Claus Eric Ott, Monika Osswald, Angela Huebner, Maja von der Hagen, Denise Emmerich, Jirko Kühnisch, Hans Morreau, Frederik J Hes, Victor F Mautner, Anja Harder, Sigrid Tinschert, Stefan Mundlos, Mateusz Kolanczyk   +14 more
doaj   +1 more source

Laparoscopic partial adrenalectomy for bilateral pheochromocytomas in a boy with von Hippel-Lindau disease [PDF]

, 2000
Objectives: In adults, increasing numbers of adrenalectomies for pheochromocytomas are performed laparoscopically. We report for the first time laparoscopic bilateral subtotal adrenalectomy for pheochromocytomas in an 8-year-old boy with von Hippel ...
Bartsch, Georg, Elsner, Romy, Janetschek, Günter, Neumann, Hartmut, Radmayr, Christian   +4 more
core   +1 more source

Review of the anatomical basis for predicting plutonium alpha particle radiation induced osteogenic cancers

The Anatomical Record, EarlyView.
Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley   +1 more source

Cell Proliferation, Movement and Differentiation during Maintenance of the Adult Mouse Adrenal Cortex

PLoS ONE, 2013
Appropriate maintenance and regeneration of adult endocrine organs is important in both normal physiology and disease. We investigated cell proliferation, movement and differentiation in the adult mouse adrenal cortex, using different 5-bromo-2 ...
Su-Ping Chang, H. Morrison, F. Nilsson, C. Kenyon, J. West, S. Morley   +5 more
semanticscholar   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Heterotopic adrenal gland in undescendent testis – Case report

Urology Case Reports, 2019
Heterotopic adrenal cortex is usually found in the kidney, retroperitoneum and spermatic cord. The adrenal gland has a dual embryonic origin: the cortex arises from the mesoderm and the medulla from ectoderm of the neural crest. Adrenal cortex and gonads
D. Anakievski, D. Malinova
doaj  

Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.

Endocrinology, 2013
Transcription factor GATA6 is expressed in the fetal and adult adrenal cortex and has been implicated in steroidogenesis. To characterize the role of transcription factor GATA6 in adrenocortical development and function, we generated mice in which Gata6 ...
M. Pihlajoki, Elisabeth Gretzinger, Rebecca S. Cochran, A. Kyrönlahti, A. Schrade, Theresa Hiller, L. Sullivan, Michael Shoykhet, E. Schoeller, Michael D. Brooks, M. Heikinheimo, D. Wilson   +11 more
semanticscholar   +1 more source

Chromogranin A in the olfactory system of the rat [PDF]

, 1990
The olfactory bulb of the rat contains chromogranin A at a similar level as the adrenal gland or the hypophysis as revealed by immunoblots. Olfactory chromogranin A also displays the same size as chromogranin A of endocrine cells.
Baker, Bulenda, Bööj, Doolittle, Efendic, Ehrlich, Fasciotto, Forss-Petter, Gerdes, Gorr, Halász, Helle, Iacangelo, Kaplan, Kawakubo, Ley, Lizardi, Nolan, O'Connor, O'Connor, O'Connor, Parmer, Reiffen, Reiffen, Ruppert, Schilling, Schmid, Simon, Simon, Somogyi, Sternberger, Switzer, Volknandt   +32 more
core   +1 more source

Intergenerational Enlargement of Human Organs as a Driver of Increased Cancer Risk?

BioEssays, EarlyView.
Identifying the environmental factors and associated mechanisms driving increased cancer incidence in younger generations is a matter of great urgency. Here, we propose and discuss a new potential mechanism: larger organ sizes in younger individuals resulting from intergenerational differences in lifestyle, diet, and environmental exposures.
Costas Koufaris, Vicky Nicolaidou
wiley   +1 more source