Results 71 to 80 of about 783,304 (397)

Heterogeneous natural history of Addison’s disease: mineralocorticoid deficiency may predominate

Endocrine Connections, 2022
Autoimmune Addison’s disease (AAD) is defined as primary adrenal insufficiency due to immune-mediated destruction of the adrenal cortex. This destruction of steroid-producing cells has historically been thought of as an irreversible process, with linear ...
Sophie Howarth, Luca Giovanelli, Catherine Napier, Simon H Pearce   +3 more
doaj   +1 more source

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S., Allolio, B., Beuschlein, Felix, Chrousos, G. P., Jaursch-Hancke, C., Karl, M., Reincke, Martin, Travis, W.   +7 more
core  

Cell-Type Specific Changes in Glial Morphology and Glucocorticoid Expression During Stress and Aging in the Medial Prefrontal Cortex. [PDF]

, 2018
Repeated exposure to stressors is known to produce large-scale remodeling of neurons within the prefrontal cortex (PFC). Recent work suggests stress-related forms of structural plasticity can interact with aging to drive distinct patterns of pyramidal ...
Bruce S. McEwen, Dani Dumitriu, Erik B. Bloss, John H. Morrison, John H. Morrison, Thomas E. Chan, Wendy Lou, William G. Janssen, Yael S. Grossman   +8 more
core   +2 more sources

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Morpho-functional state of human fetuses’ adrenal cortex during influence of maternal infection

Journal of Education, Health and Sport, 2018
Aim of study. To reveal influence of maternal infection on morpho-functional state of fetuses’ adrenal cortex. Methods. The material was obtained during sectional studies, which were conducted on the basis of the "Kharkiv Regional Clinical Perinatal ...
Vira Tovazhnianska
doaj   +3 more sources

CONGENITAL ADRENAL CORTEX HYPERPLASIA IN A NEWBORN (CLINICAL CASE)

Неонатологія, хірургія та перинатальна медицина, 2019
Congenital adrenal cortex hyperplasia combines a group of monogenic diseases with an autosomal recessive fashion based on defects in enzymes or transport proteins involved in adrenal steroidogenesis.
N.M. Kretsu, L.V Kolyubakina, T.N. Kretsu, L.F. Balytska   +3 more
doaj   +1 more source

Comparative study on the effects of type 1 and type 2 diabetes on structural changes and hormonal output of the adrenal cortex in male Wistar rats

Journal of Diabetes and Metabolic Disorders, 2013
IntroductionDiabetes is one of the most common endocrine disorders characterized by hyperglycemia due to defects in insulin secretion, insulin function, or both.
Zohreh Elahi-Moghaddam, M. Behnam-Rassouli, N. Mahdavi-Shahri, Roya Hajinejad-Boshroue, Elaheh Khajouee   +4 more
semanticscholar   +1 more source

Interrelations of the endocrine organs [PDF]

, 1924
Thesis (M.A.)--Boston ...
Birrell, Ethel Jane
core   +1 more source

Targeting SPHK1 in macrophages remodels the tumor microenvironment and enhances anti‐PD‐1 immunotherapy efficacy in colorectal cancer liver metastasis

Cancer Communications, EarlyView.
Abstract Background Colorectal cancer liver metastasis (CRLM) is characterized by an immunosuppressive microenvironment and a blunted response to immunotherapy. Notably, tumor‐associated macrophages (TAMs) play a critical role in modulating immune responses and exhibit significant heterogeneity in CRLM.
Yizhi Zhan, Jinsong Xu, Zhanqiao Zhang, Yating Hu, Yongsheng Li, Junying Qian, Yunyan Ling, Dehua Wu, Haijun Deng, Guoxin Li, Zhiyong Shen, Yuan Fang   +11 more
wiley   +1 more source

MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation. [PDF]

, 2018
Melanocortin 2 receptor accessory protein (MRAP) is a single transmembrane domain accessory protein and a critical component of the hypothamo-pituitary-adrenal axis.
Chan, LF, Charalambous, M, Clark, AJL, Guasti, L, Hussain, M, King, PJ, Metherell, LA, Novoselova, TV   +7 more
core   +2 more sources