Results 71 to 80 of about 79,543 (252)

Using microwave thermal ablation to develop a subtotal, cortical-sparing approach to the management of primary aldosteronism

International Journal of Hyperthermia, 2019
Objective: To investigate the feasibility and efficacy of localized, subtotal, cortical-sparing microwave thermal ablation (MTA) as a potential curative management for primary aldosteronism.
Padraig T. Donlon, Hojjatollah Fallahi, Warren L. Beard, Atif Shahzad, Lindsay Heflin, Whitney Cox, Brooke Bloomberg, James D. Lillich, Chanran K. Ganta, Gerard J. O’Sullivan, Giuseppe Ruvio, Paula M. O’Shea, Martin O’Halloran, Punit Prakash, Michael Conall Dennedy   +14 more
doaj   +1 more source

Childhood Maltreatment and Cognitive Functioning in Bipolar Disorder: A Systematic Review and Meta‐Analysis

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Aims Characterising the association between childhood maltreatment (CM) and cognitive functioning in bipolar disorder (BD) is crucial for improving the understanding of how early environmental risk factors impact the presentation of the disorder.
Natalia E. Fares‐Otero, Anaid Pérez‐Ramos, Ricardo Lopez‐Escribano, Sara Martin‐Parra, Luis Alameda, Sarah L. Halligan, Kamilla Woznica Miskowiak, Eduard Vieta   +7 more
wiley   +1 more source

International Evidence‐Based Guidelines for Traditional Chinese Medicine Management of Allergic Rhinitis

Allergy, EarlyView.
ABSTRACT Allergic rhinitis (AR) is a prevalent chronic condition that significantly impacts patients' quality of life and poses challenges to effective management. Traditional Chinese medicine (TCM) offers a holistic approach, emphasizing syndrome differentiation, individualized care, and natural treatment strategies.
Qin‐Wei Fu, Peng Liu, Yan Ruan, Xin‐Rong Li, Lan‐Zhi Zhang, Sha‐Sha Yang, Feng Chai, Ji Chen, Qiao‐Yan Chen, Shu‐Cheng Chen, Wen‐Yong Chen, Yong‐Na Chen, Hong‐Bin Cheng, Lei Cheng, Lu‐Jia Cui, Ke‐Bin Deng, Cai‐Shan Fang, Rong‐Chang Feng, Li Fu, Wen‐Yang Fu, Jian‐Ying Gao, Hong Guo, Miao He, Ko‐Hsin Hu, Chun‐Jiang Huang, He‐Yin Huang, Lu‐Yun Jiang, Feng‐Ying Qiao, Hui Leng, Yun‐Ying Li, Chun‐Song Liu, Da‐Xin Liu, Jian‐Hua Liu, Jin‐Hui Liu, Jing Liu, Min Liu, Wei‐Ting Liu, Yuan‐Xian Liu, Yang Liu, Ying Liu, Zhi‐Qing Liu, Qiu‐Lan Luo, Yu Ma, De‐Hong Mao, Juan Meng, Kai‐Yun Pang, Shun‐Lin Peng, Xuan‐Fu Tong, Ji Wang, Jia‐Xi Wang, Jun‐Ge Wang, Ren‐Zhong Wang, Shi‐Zhen Wang, Ji‐Yan Xia, Hui Xie, Qiang Xie, Yan Xie, Da‐Jing Xiong, Zhan‐Feng Yan, Hui Yang, Da‐Zheng Zhang, Fu‐Bing Zhang, Shi‐Peng Zhang, Zhi‐Cheng Zhang, Ji‐Ping Zhao, Yu Zhao, Yun Zheng, Dan‐Zhu Zhong, Li Zhou, Valentin Mikhailovich Knyazev, Irina Viktorovna Kostrova, Wing‐Fai Yeung, Qi Wang, De‐Yun Wang, Qin‐Xiu Zhang   +74 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

TRP canonical 4 and/or 5 channel inhibition reduces aversion‐ and increases reward‐responding in chronically stressed mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Pharmacological inhibition of TRPC4 and/or TRPC5 channels reduces Pavlovian aversion memory in stressed mice and reduces amygdala reactivity to aversion in humans with depression. The aims of this mouse study were to improve understanding of these anxiolytic processes, determine whether there are corrective effects on ...
Giulia Poggi, Deniz Queisser, Alena Senn, Hannes Sigrist, Diana Kúkeľová, Lorraine Madur, Nagiua Cuomo‐Haymour, Mélisse Robert, Sophie Schmid, Adrián Portalés, Sophie Simard, Naguib Mechawar, Bastian Hengerer, Stefan Just, Christopher R. Pryce   +14 more
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source

Neonatal adrenal hemorrhage presenting as late onset neonatal jaundice

Journal of Indian Association of Pediatric Surgeons, 2009
Clinical manifestations of adrenal hemorrhage vary depending on the degree and rate of hemorrhage, as well as the amount of adrenal cortex compromised by hemorrhage.
Qureshi Umar, Ahmad Nisar, Rasool Akhter, Choh Suhail   +3 more
doaj  

Pituitary-adrenal axis dysfunction induced by tislelizumab immunotherapy for non-small cell lung cancer: a case series and literature review

BMC Pulmonary Medicine
Background Adverse events of secondary adrenal insufficiency caused by anti-PD-1 immune agents are relatively rare in clinical practice, so in this article, we retrospectively analyzed three patients who suffered secondary adrenal cortex dysfunction ...
Jiayi Wang, Huanrong Lan, Xiaowei Mao, Yefeng Chen   +3 more
doaj   +1 more source

Cerebrovascular Function in Women With Polycystic Ovary Syndrome: A Pilot Multi‐Parameter Magnetic Resonance Imaging Study

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Polycystic ovary syndrome (PCOS) is associated with an increased risk of cerebrovascular disease, but the effects on cerebrovascular function are unknown. In this pilot study, we sought to compare cerebrovascular perfusion, pulsatility, reactivity and metabolism between women with PCOS and healthy volunteers using MRI, and ...
Melissa E. Wright, Cory T. Richards, Saajan Davies, Rachel N. Lord, D. Aled Rees, Kevin Murphy   +5 more
wiley   +1 more source