Results 141 to 150 of about 187,564 (336)

A Genome‐Wide Association Study of Colorectal Cancer Mortality Outcomes Among Individuals of African and Admixture Ancestry

Molecular Carcinogenesis, EarlyView.
ABSTRACT African Americans have the highest colorectal cancer (CRC) mortality rates in the United States. We performed the first genome‐wide association study (GWAS) of overall and CRC‐specific mortality among African Americans with incident CRC to identify genetic contributors to CRC outcomes.
Thomas Lawler, Jirong Long, Rene Welch, Irene Ong, Oluwatoyosi Ogunmuyiwa, Rida A. Khatri, Martha Shrubsole, Shaneda Warren Andersen   +7 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

MRI-based adrenal gland volume is associated with cardiovascular alterations in individuals without prior cardiovascular disease

Scientific Reports
Aim of this study was to analyse the associations of cardiovascular health and adrenal gland volume as a rather new imaging biomarker of chronic hypothalamic–pituitary–adrenal (HPA) axis activation.
Esther Askani, Susanne Rospleszcz, Roberto Lorbeer, Charlotte Wintergerst, Katharina Müller-Peltzer, Johanna Nattenmüller, Dunja Hasic, Ricarda von Krüchten, Elias Kellner, Marco Reisert, Wolfgang Rathmann, Annette Peters, Christopher L. Schlett, Fabian Bamberg, Corinna Storz   +14 more
doaj   +1 more source

Morphological and functional manifestations of rat adrenal-cortex response to sodium bromide administration under hypodynamic stress [PDF]

Functional and morphological manifestations of adrenal cortex response to hypodynamia (2-hr immobilization on an operating table) under the influence of bromine preparations were studied. The sodium bromide was administered intraperitoneally in 100, 250,
Kirichek, L. T., Zholudeva, V. I.
core   +1 more source

Upon the Endocrine Organ Weight on the View Point of Relationship Between Thymus and Adrenal Gland in Albino Rats

, 1960
Sadayoshi YOKOH, Tadashi TENDA, M. Masaki, Hirofumi SAKAGAMI, Naonori KIKKAWA   +4 more
openalex   +2 more sources

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag, Michael J. Murphy, Nicola Z. Hobbs, Michela Leocadi, Kate Fayer, Olivia Thackeray, Johan Gobom, Marc Ciosi, Amanda Heslegrave, Henrik Zetterberg, Douglas R. Langbehn, Darren G. Monckton, Edward J. Wild, Sarah J. Tabrizi, Rachael I. Scahill   +14 more
wiley   +1 more source

Role of Sleep Disturbances and Diabetes‐Related Distress on Glycemic Control: A Path Analysis

Research in Nursing &Health, EarlyView.
ABSTRACT Despite advancements in diabetes management technology, many patients with type 2 diabetes (T2D) struggle to achieve optimal glycemic control. Sleep disorders such as obstructive sleep apnea (OSA) and insomnia are common in T2D and linked to poor glycemic control. Insomnia, particularly with short sleep duration, may worsen glycemic control by
Bomin Jeon, Faith S. Luyster, Eileen R. Chasens   +2 more
wiley   +1 more source

The Sooner, the Better: Neuroprotective Strategies in Fetuses With Congenital Heart Disease

Prenatal Diagnosis, EarlyView.
ABSTRACT Congenital heart disease (CHD) is the most frequent congenital malformation at birth and is associated with neurodevelopmental impairments. Alterations in cardiovascular physiology can lead to reduced cerebral blood perfusion and oxygenation, which negatively affects brain growth and maturation.
Maaike Nijman, Mirthe E. M. van der Meijden, Johannes M. P. J. Breur, Raymond Stegeman, Nicolaas J. G. Jansen, Mireille N. Bekker, Manon J. N. L. Benders, Nathalie H. P. Claessens   +7 more
wiley   +1 more source

Preferential localization of a vesicular monoamine transporter to dense core vesicles in PC12 cells. [PDF]

, 1994
Neurons and endocrine cells have two types of secretory vesicle that undergo regulated exocytosis. Large dense core vesicles (LDCVs) store neural peptides whereas small clear synaptic vesicles store classical neurotransmitters such as acetylcholine ...
Edwards, RH, Evans, CJ, Liu, Y, Nirenberg, MJ, Pickel, VM, Schweitzer, ES   +5 more
core  

Additional file 7 of Exploring the roles of fecundity-related long non-coding RNAs and mRNAs in the adrenal glands of small-tailed Han Sheep

, 2020
Qing Xia, Qiuling Li, Shangquan Gan, Xiaofei Guo, Xiaosheng Zhang, Jinlong Zhang, Mingxing Chu   +6 more
openalex   +1 more source