Results 151 to 160 of about 86,771 (245)
Biosynthetic enzyme activities and catecholamines in adrenal glands of genetic and experimental hypertensive rats. [PDF]
H. Grobecker +2 more
openalex +1 more source
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Characterization of Cytokine Treatment on Human Pancreatic Islets by Top‐Down Proteomics
ABSTRACT Type 1 diabetes (T1D) results from autoimmune‐mediated destruction of insulin‐producing β cells in the pancreatic islet. This process is modulated by pro‐inflammatory cytokine signaling, which has been previously shown to alter protein expression in ex vivo islets.
Ashley N. Ives +8 more
wiley +1 more source
Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley +1 more source
HISTAMINE IN ADRENAL GLAND : DISTRIBUTION AND CONTENT DURING GLOWTH
Yasuo Endo, Yasumi Ogura
openalex +1 more source
Abstract Background Pheochromocytoma is a rare catecholamine‐secreting tumor that often presents with symptoms such as hypertension, palpitations, and sweating due to excessive hormone production. In some cases, the catecholamine‐induced vasoconstriction and hypercoagulability associated with pheochromocytomas can lead to cerebrovascular accidents and ...
Mohannad N. AbuHaweeleh +6 more
wiley +1 more source
Renal cell carcinoma with atypical omental metastasis: A case report and literature review
Abstract Background Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, with common metastatic sites including the lungs, bones, liver, and brain. Omental metastasis is exceedingly rare and usually occurs postoperatively. Fumarate hydratase‐deficient (FH‐deficient) RCC, a recently classified and highly aggressive subtype of ...
Andrew Jing +4 more
wiley +1 more source
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai +11 more
wiley +1 more source

