Results 131 to 140 of about 116,596 (358)

Clinical Outcomes of Different Generation EGFR TKIs in Susceptible EGFR‐Mutated Advanced Nonsmall‐Cell Lung Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are indicated for advanced lung adenocarcinoma patients harboring susceptible EGFR mutations. The aim of this retrospective study was to compare the effectiveness of different generations of EGFR TKIs.
Chia‐Yu Kuo, Tien‐Chi Huang, Chih‐Jen Yang, Mei‐Hsuan Lee, Jui‐Ying Lee, Ying‐Ming Tsai, Kuan‐Li Wu, Cheng‐Hao Chuang, Inn‐Wen Chong, Jen‐Yu Hung   +9 more
wiley   +1 more source

Intratumoral Nerve Phased Development: A Promising Therapeutic Target

Medicine Bulletin, EarlyView.
ABSTRACT The nervous system has emerged as a critical regulator of tumor biology, engaging in dynamic crosstalk with cancer cells. Although the protumorigenic role of innervation is well established, increasing attention is now directed toward reciprocal influences—how tumors actively shape and remodel local nerve networks within the tumor ...
Xiangxian Che, Hang Wang, Han Wang, Yi‐Zhou Jiang   +3 more
wiley   +1 more source

Laparoscopic adrenalectomy for malignant disease – Technical feasibility and oncological results [PDF]

Einstein (São Paulo), 2007
Objective: Laparoscopic resection is the gold standard for treatmentof benign adrenal lesions. Laparoscopic resection of malignant lesions,however, is controversial, and there are only limited series publishedin the literature.
Marcos Tobias Machado, Rodrigo Alves Tristão, Matheus Neves Ribeiro da Silva, Eric Roger Wroclawski   +3 more
doaj  

Harnessing Gut Microbiome–Brain–Liver Crosstalk: Novel Therapeutic Strategies for Metabolic Dysfunction‐Associated Steatotic Liver Disease

Medicine Bulletin, EarlyView.
This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao, Ruolan Li, Jingdong Zhao, Ruiqi Sun, Shuo Zhang, Qiong Pan, Hongyan Lu, Jin Chai   +7 more
wiley   +1 more source

Treatment-related neuroendocrine prostatic carcinoma masquerading as a pheochromocytoma: an unusual presentation

Human Pathology Reports
Prostatic adenocarcinoma metastases to adrenal gland are rare and can be difficult to distinguish from primary adrenal neoplasms, particularly pheochromocytoma, especially in the post- treatment setting where neuroendocrine transformation is possible. We
Priscila Dias Goncalves, Peter M. Sadow, Miranda E. Machacek   +2 more
doaj   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Giant adrenal myelolipoma with a spontaneous rupture: report of a case [PDF]

Einstein (São Paulo), 2009
Myelolipoma is a benign tumor of the adrenal cortex, which is non-functioning and often asymptomatic. It is generally diagnosed in imaging tests by chance.
Sergio Renato Pais Costa, Sergio Henrique Couto Horta, Alexandre Cruz Henriques   +2 more
doaj  

Ganglioneuroma Always A Histopathological Diagnosis [PDF]

, 2011
Neuroblastoma, ganglioneuroblastoma and ganglioneuroma arise from sympathetic tissue in the neck, posterior mediastinum, adrenal gland, retroperitoneum and pelvis Ganglioneuromas are commonly seen in childhood.
K, Balaiah, S, Gnana Prakash, Shetty, Prasad K, Shetty, Prasanna K   +3 more
core   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

Phytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Atypical presentation of pheochromocytoma as acute ischemic stroke and pulmonary embolism, a case report

UroPrecision, EarlyView.
Abstract Background Pheochromocytoma is a rare catecholamine‐secreting tumor that often presents with symptoms such as hypertension, palpitations, and sweating due to excessive hormone production. In some cases, the catecholamine‐induced vasoconstriction and hypercoagulability associated with pheochromocytomas can lead to cerebrovascular accidents and ...
Mohannad N. AbuHaweeleh, Ahmad Yousef Al‐maslamani, Majd A. AbuAlrob, Abdelrahman Elsayed, Mahmoud Altayyan, Osama Khalil, Ahmad Abdulhadi   +6 more
wiley   +1 more source