Results 131 to 140 of about 386,587 (303)

Phase II Study of Cisplatin/Gemcitabine Plus Necitumumab for Squamous NSCLC After ICI‐Platinum Therapy (WJOG14120L)

open access: yesCancer Science, EarlyView.
WJOG14120L NESSIE evaluated cisplatin, gemcitabine, and necitumumab (CGN) as second‐line therapy after ICI‐based treatment in 46 patients with advanced squamous NSCLC. ORR was 26.1%, DCR 87.0%, and median PFS 4.4 months. Although the predefined ORR threshold was not met, CGN showed modest antitumor activity with manageable toxicity.
Hiroshige Yoshioka   +15 more
wiley   +1 more source

Endothelial cyst of the adrenal gland: A rare case report

open access: yesSAGE Open Medical Case Reports
Adrenal gland cysts are rare and uncommon manifestations. Mostly asymptomatic, discovered incidentally during radiological studies or at autopsy, or without characteristic symptoms.
Khadija Laasri   +8 more
doaj   +1 more source

Adrenal Gland (Labeled)

open access: yes
Adrenal ...
Royal College of Surgeons of Ireland (RCSI)
core  

Japanese Society for Hereditary Tumors Guidance: Hereditary Cancer Syndromes With Multigene Panel Testing, 2025 Edition

open access: yesCancer Science, EarlyView.
Schematic of the clinical algorithm for diagnosing hereditary cancer syndromes using MGPT. ABSTRACT In March 2025, the Japanese Society for Hereditary Tumors and the Ministry of Health, Labour and Welfare (MHLW) Research on Promotion of Cancer Control Program Grant Number JPMH 23EA1037 published the “Japanese Society for Hereditary Tumors Guidance ...
Reiko Yoshida   +66 more
wiley   +1 more source

Endoscopic Ultrasound‐Guided Ethanol Ablation for Benign Insulinoma: A Single‐Centre Experience and Literature Review

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objectives Insulinoma is a predominantly benign pancreatic neuroendocrine tumour that is traditionally managed surgically. However, surgical invasiveness and anaesthesia‐related risks limit its applicability in selected patients. Endoscopic ultrasound (EUS)‐guided ethanol ablation has emerged as a minimally invasive alternative.
Yuchao Wu   +15 more
wiley   +1 more source

Secondary Adrenal Insufficiency Presenting With Severe Hyponatremia in an Elderly Patient With Primary Aldosteronism Suggesting Underlying Autonomous Cortisol Secretion

open access: yesClinical Case Reports
Possible unrecognized cortisol autonomy in primary aldosteronism may suppress the hypothalamic–pituitary–adrenal axis. Under physiological stress, this may contribute to secondary adrenal insufficiency and severe hyponatremia.
Minami Toda   +5 more
doaj   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton   +4 more
wiley   +1 more source

Development and evolution of the adrenal gland and its homologs in teleosts, anurans, chelonians and birds

open access: yes, 2008
The morphology, histology, histochemistry and immunohistochemistry of the adrenal gland or its homolog were examined during development and in the adults of species belonging to the teleost fishes, anuran amphibians, chelonian reptiles and birds (chicken)
CHIMENTI, Claudio, ACCORDI, Fiorenza
core  

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