Results 41 to 50 of about 29,100 (161)

Congenital adrenal hyperplasia in men: classical form. Clinical case

Mìžnarodnij Endokrinologìčnij Žurnal, 2021
Recently, in the foreign scientific literature there have been reports that boys and young men with the classic virile form of congenital adrenal hyperplasia or congenital dysfunction of the adrenal cortex as a result of inadequate glucocorticoid therapy
P.M. Liashuk, N.I. Stankova, R.P. Liashuk   +2 more
doaj   +1 more source

The aporetic dialogues of Modena on gender differences: Is it all about testosterone? Episode II: Empathy

Andrology, EarlyView.
Abstract The exploration of gender differences in non‐andrological fields was the core focus of a series of discussions, which took place at the Endocrinology Unit in Modena, Italy in the form of the aporetic dialogue of ancient Greece. This second episode reports the transcript of the actual debate on testosterone's role in defining empathic behavior ...
Giulia Brigante, Clara Lazzaretti, Ali Ahmad, Massimiliano Colzani, Filippo Vignali, Michele Zoli, Manuela Simoni   +6 more
wiley   +1 more source

Homozygous disruption of P450 side-chain cleavage (CYP11A1) is associated with prematurity, complete 46,XY sex reversal, and severe adrenal failure [PDF]

, 2005
Disruption of the P450 side-chain cleavage cytochrome (P450scc) enzyme due to deleterious mutations of the CYP11A1 gene is thought to be incompatible with fetal survival because of impaired progesterone production by the fetoplacental unit.
Achermann, JC, Hiort, O, Holterhus, PM, Hoppe, U, Marschke, C, Partsch, CJ, Riepe, FG, Struve, D, Werner, R   +8 more
core   +1 more source

Spontaneous Intestinal Perforation in Extremely Premature Infants Exposed to Early Low‐Dose Hydrocortisone

Acta Paediatrica, EarlyView.
ABSTRACT Aim To assess the occurrence of spontaneous intestinal perforation (SIP) in < 28 weeks' gestational age (GA) infants exposed to early low‐dose hydrocortisone (ELH) to reduce the risk of bronchopulmonary dysplasia (BPD). Additionally, the risk of SIP was assessed in infants exposed to early concomitant treatment with ibuprofen for persistent ...
Gilles Cambonie, Anais Jouffrey, Benoit Tessier, Clémentine Combes, Angelo Polito, Arthur Gavotto   +5 more
wiley   +1 more source

Acute onset neurological deficits and hypocalcaemia associated with nutritional secondary hyperparathyroidism in three juvenile servals (Leptailurus serval)

Australian Veterinary Journal, EarlyView.
Nutritional secondary hyperparathyroidism is a metabolic disorder caused by an imbalance in calcium homeostasis and is typically associated with the feeding of a calcium‐deficient diet. Nutritional secondary hyperparathyroidism has been reported in domestic species, including cats and dogs, as well as captive carnivores and wildlife including lions ...
JL Austen, JW Wheelahan, J O'Dwyer, S Beths, NL Rourke, BR Gardner   +5 more
wiley   +1 more source

GNAS mutation is an unusual cause of primary adrenal insufficiency: a case report

BMC Pediatrics, 2022
Background Primary adrenal insufficiency in children has non-specific and extensive clinical features, so the diagnosis of its etiology is complex and challenging.
Yajie Tong, Dongmei Yue, Ying Xin, Dan Zhang   +3 more
doaj   +1 more source

Salivary Testosterone, Androstenedione and 11‐Oxygenated 19‐Carbon Concentrations Differ by Age and Sex in Children

Clinical Endocrinology, EarlyView.
ABSTRACT Background The diagnosis and management of childhood adrenal disorders is challenging. Clinical markers of hormone excess or deficiency may take months to manifest, and traditional biomarkers correlate only partially with clinical outcomes.
Julie Park, Andrew Titman, Orla Bright, Silothabo Dliso, Alena Shantsila, Gregory Y. H. Lip, Jo Adaway, Brian Keevil, Daniel B. Hawcutt, Joanne Blair   +9 more
wiley   +1 more source

Normal sex differences in prenatal growth and abnormal prenatal growth retardation associated with 46,XY disorders of sex development are absent in newborns with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Biology of Sex Differences, 2011
Background Congenital adrenal hyperplasia due to 21-hydroxylase deficiency is the most common presentation of a disorder of sex development (DSD) in genetic females. A report of prenatal growth retardation in cases of 46,XY DSD, coupled with observations
Chalmers Laura J, Doherty Paul, Migeon Claude J, Copeland Kenneth C, Bright Brianna C, Wisniewski Amy B   +5 more
doaj   +1 more source

Novel associations in disorders of sex development: findings from the I-DSD registry [PDF]

, 2013
Context: The focus of care in disorders of sex development (DSD) is often directed to issues related to sex and gender development. In addition, the molecular etiology remains unclear in the majority of cases.<p></p> Objective: To report ...
Ahmed, Ahmed, Ahmed, Ahmed, Akre, Antonio Balsamo, Bangsbøll, Bebermeier, Berger, De Groote, Dolk, Duguid, Feyza Darendeliler, Flück, Gottlieb, Guerrier, Hiort, Hughes, Hughes, Hughes, Ieuan Hughes, Jillian Bryce, Jipu Jiang, Kathryn Cox, Kreidberg, Köhler, Laura Audi, Lidka Lisa, Martina Rodie, Martine Cools, Melià, Miles, Mona Alkhawari, Mona Ellaithi, Morcel, Nabhan, Nils Krone, Nowaczyk, Olaf Hiort, Olle Soder, Ono, Pang, Paul-Martin Holterhus, Peter Wieacker, Porter, Richard Sinnott, S. Faisal Ahmed, Silvano Bertelloni, Stenvert Drop, Sun, Telvi, Thyen, Tokgoz, Tosson, Tulay Guran, Wiebke Arlt, Yang, Yinon, Yves Morel   +58 more
core   +3 more sources

Delayed Bone Maturation and Extended Growth Phase as Distinctive Features of 17α‐Hydroxylase/17,20‐Lyase Deficiency: A Retro‐Prospective Study of a Large Patient Cohort

Clinical Endocrinology, EarlyView.
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele, Flávia A. Costa‐Barbosa, Marivânia Costa‐Santos, Rafael L. Batista, Lívia M. Mermejo, Berenice B. Mendonça, Margaret de Castro, Gil Guerra‐Júnior, Claudio E. Kater, Brazilian Congenital Adrenal Hyperplasia Multicenter Study Group (BCAHMSG)   +9 more
wiley   +1 more source