Results 31 to 40 of about 117,431 (260)

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

open access: yesAdvanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong   +14 more
wiley   +1 more source

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

open access: yesThe Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi   +21 more
wiley   +1 more source

Difficulties in the radiological diagnosis of mature adrenal teratoma mimicking neuroblastoma in a child [PDF]

open access: yesDigital Diagnostics
The most common adrenal tumor in young children is neuroblastoma, which can be difficult to differentiate from other conditions such as nephroblastoma, adrenal hemorrhage, angiomyolipoma, myelolipoma, and adenoma.
Ekaterina S. Shchelkanova   +2 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

open access: yesAdvanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang   +12 more
wiley   +1 more source

Clinicopathological characteristics of adrenal tumors in older adults: a cohort study

open access: yesFrontiers in Endocrinology
IntroductionTo investigate age-specific characteristics of adrenal tumors in older adults and to identify predictors for adrenal malignancy.MethodsInpatients ≥60 years old with adrenal tumor evaluated at a large medical center between January 2011 and ...
Yuanyuan Tang   +6 more
doaj   +1 more source

A large adrenocortical adenoma surrounded with a renal arteriovenous malformation

open access: yesIJU Case Reports, 2021
Introduction Large adrenal adenomas are clinically rare. We report a case of a large adrenal adenoma with a renal arteriovenous malformation, mimicking a malignant adrenal tumor in preoperative imaging.
Takato Nishino   +7 more
doaj   +1 more source

A BSCB‐Penetrating Nanoplatform for Enhanced Luteolin Delivery in PRMT2‐Targeted Epigenetic Therapy of Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
In this work, MSN‐BO@LUT penetrates the blood‐spinal cord barrier for luteolin delivery in spinal cord injury. The nanodrug suppresses neuroinflammation and promotes functional recovery of the spinal cord. Mechanistically, luteolin targets protein arginine N‐methyltransferase (PRMT2) to decrease toll‐like receptor 4 (TLR4) methylation, thereby ...
Yixuan Wang   +11 more
wiley   +1 more source

Adenomatoid tumor of the adrenal Gland: A case report and review of literature

open access: yesHuman Pathology Reports
Adenomatoid tumor is a rare benign neoplasm that arises from mesothelial cells. It is commonly found in the genital tract, and the adrenal gland is an is an extremely rare location for adenomatoid tumor.
Elsayed Ibrahim   +4 more
doaj   +1 more source

Management of Bilateral Adrenal Metastases from Hepatocellular Carcinoma: A Case Report

open access: yesKaohsiung Journal of Medical Sciences, 2005
The adrenal glands rarely are an extrahepatic site for metastasis from hepatocellular carcinoma (HCC). Once identified, adrenal metastasis requires aggressive management, due to the risk of rupture and internal hemorrhaging. Disease management of adrenal
Meng-Hsuan Hsieh   +2 more
doaj   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

open access: yesAdvanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang   +21 more
wiley   +1 more source

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