Results 191 to 200 of about 184,471 (381)

Onset and duration of beta‐adrenergic receptor blockade following single oral dose acebutolol hydrochloride (Sectral). [PDF]

, 1979
R D Watson, WA Littler
openalex   +1 more source

Investigating Dopamine Replacement–Associated Fluctuations in Cognition and Mood in Cognitively Unimpaired Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor fluctuations, characterized by variability in mood and cognition, are prevalent in advanced Parkinson's disease (PD), but less is known about these fluctuations in early PD. Objective The objective was to characterize fluctuations in cognition and mood in early PD without cognitive impairment.
Abhimanyu Mahajan, Christopher B. Morrow, Joseph Seemiller, Kelly A. Mills, Gregory M. Pontone   +4 more
wiley   +1 more source

Redox and proteolytic regulation of cardiomyocyte β₁-adrenergic receptors - a novel paradigm for the regulation of catecholamine responsiveness in the heart. [PDF]

Front Immunol, 2023
Steinberg SF.
europepmc   +1 more source

Treatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform

Movement Disorders, EarlyView.
Abstract Background There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...
Cristina Gonzalez‐Robles, Dilan Athauda, Thomas R. Barber, Roger A. Barker, David T. Dexter, Susan Duty, Romy Ellis‐Doyle, Sonia Gandhi, Joel Handley, Edwin Jabbari, Keith Martin, Kevin McFarthing, Georgia Mills, Heather Mortiboys, Stephen Mullin, Rebecca Petty, Esther Sammler, Paula Scurfield, Simon R.W. Stott, George K. Tofaris, Li Wei, Caroline H. Williams‐Gray, Alan Wong, Marie‐Louise Zeissler, Richard K. Wyse, Camille B. Carroll, Thomas Foltynie, Oliver Bandmann, Anthony H.V. Schapira, on behalf of the EJS ACT‐PD Consortium   +29 more
wiley   +1 more source

Recent Developments in the Optical Control of Adrenergic Signaling

Medicinal Research Reviews, EarlyView.
ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi, Yangzhi Cao, Maikel Wijtmans, Henry F. Vischer, Rob Leurs   +4 more
wiley   +1 more source

The effect of beta adrenergic receptor blockade on the vasodilator response in the forearm to voluntary hyperventilation

, 1966
I. Brick, K.J. Hutchison, I. C. Roddie
openalex   +1 more source

Properties of purified cholinergic and adrenergic receptors [PDF]

, 1977
Antonio Prince
openalex   +1 more source

Progress in Molecular Imprinting—From Inhibition of Enzymatic Activity to Regulation of Cellular Pathways

Medicinal Research Reviews, EarlyView.
ABSTRACT Molecular imprinting is a very powerful tool in life science. The research areas benefiting from a wide range of capabilities of molecularly imprinted polymeric nanoparticles (nanoMIPs) include sample preparation, extraction, sensing/detection, diagnostics, and drug delivery.
Milada Vodova, Jaroslava Bezdekova, Marketa Vaculovicova   +2 more
wiley   +1 more source

The differences in the adrenergic receptors of proximal urethra between sexes. [PDF]

Tzu Chi Med J, 2023
Hsieh PC, Chang SJ, Chang HH, Yang SS.
europepmc   +1 more source

Enhancing Heart Health: Expanding the Use of SGLT2 Inhibitors in Cardiovascular Disease

Medicine Advances, EarlyView.
SGLT2 inhibitors offer multifaceted cardiovascular benefits, including improved cardiac metabolism, reduced preload and afterload, and decreased myocardial infarction risk. These effects are driven by renoprotection, anti‐inflammatory properties, improved mitochondrial function, osmotic diuresis, and glycemic control. Together, these mechanisms support
Manahil Mubeen, Aasiya Shahbaz Sakarwala, Arif Imdad Bijarani, Muhammad Taha Kamal   +3 more
wiley   +1 more source