Results 131 to 140 of about 1,396,034 (289)
Cancer Medicine, 2019 To identify prognostic genes which were associated with adrenocortical carcinoma (ACC) tumor microenvironment (TME).
Xiao Li +5 more
semanticscholar +1 more source
New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells
ClinicsOBJECTIVES: Transcription Factor 21 represses steroidogenic factor 1, a nuclear receptor required for gonadal development, sex determination and the regulation of adrenogonadal steroidogenesis.
Monica Malheiros França +3 more
doaj +1 more source
Identification of four hub genes associated with adrenocortical carcinoma progression by WGCNA
PeerJ, 2019 Background Adrenocortical carcinoma (ACC) is a rare and aggressive malignant cancer in the adrenal cortex with poor prognosis. Though previous research has attempted to elucidate the progression of ACC, its molecular mechanism remains poorly understood ...
Wangxiao Xia +8 more
semanticscholar +1 more source
Indian Journal of Pathology and Microbiology, 2019 Ectopic adrenocortical tissue may be present in many anatomical localizations. Hyperplasia, adenoma or carcinoma can occasionally develop from the ectopic adrenal tissue. Therefore, it should be surgically excised when it is detected.
Ismail Saygin +3 more
doaj +1 more source
Automated Selection of Hotspots (ASH): enhanced automated segmentation and adaptive step finding for Ki67 hotspot detection in adrenal cortical cancer [PDF]
, 2014 BACKGROUND: In prognosis and therapeutics of adrenal cortical carcinoma (ACC), the selection of the most active areas in proliferative rate (hotspots) within a slide and objective quantification of immunohistochemical Ki67 Labelling Index (LI) are of ...
Dinjens, W.N.M. (Winand) +7 more
core +5 more sources
Journal of Clinical Medicine, 2019 Mitotane is used as a post-operative adjuvant treatment for patients with adrenocortical carcinoma. Monitoring of plasma mitotane concentrations is recommended, but we do not know what impact target concentrations have on patient outcome.
S. Puglisi +20 more
semanticscholar +1 more source
Journal of Immunotherapy for Cancer, 2018 BackgroundWe assessed the efficacy and safety of avelumab, an anti-programmed death ligand 1 (PD-L1) antibody, in patients with previously treated metastatic adrenocortical carcinoma (mACC).MethodsIn this phase 1b expansion cohort, patients with mACC and
C. Le tourneau +11 more
semanticscholar +1 more source
Adrenal insufficiency caused by bilateral adrenal metastases - a rare treatable cause for recurrent nausea and vomiting in metastatic breast cancer [PDF]
, 2006 Background: Nausea and vomiting are common symptoms in patients with malignant disease. Several, sometimes rare causes have to be considered to decide the right treatment.
Bausewein, Claudia +2 more
core +1 more source
Plasma steroid metabolome profiling for the diagnosis of adrenocortical carcinoma.
European Journal of Endocrinology, 2019 Objective Current workup for the pre-operative distinction between frequent adrenocortical adenomas (ACAs) and rare but aggressive adrenocortical carcinomas (ACCs) combines imaging and biochemical testing.
Sophie Schweitzer +9 more
semanticscholar +1 more source
A Rare Adrenal Incidentaloma That Mimics Adrenocortical Carcinoma
Case Reports in Surgery, 2018 Objective. We present a case of an adrenal hemangioma, an uncommon cause of an adrenal mass, and review the clinical presentation, work-up, and management of adrenal incidentalomas. Background.
Kedar Lavingia +5 more
doaj +1 more source