Results 71 to 80 of about 92,029 (171)

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

open access: yesCell Reports, 2018
Summary: This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smoking and/or human papillomavirus (HPV). SCCs harbor 3q, 5p, and
Joshua D. Campbell   +784 more
doaj   +1 more source

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

open access: yesCell Reports, 2018
Summary: Beyond sample curation and basic pathologic characterization, the digitized H&E-stained images of TCGA samples remain underutilized. To highlight this resource, we present mappings of tumor-infiltrating lymphocytes (TILs) based on H&E images ...
Joel Saltz   +740 more
doaj   +1 more source

Frequency dependence favours social plasticity and facilitates socio‐eco‐evolutionary feedback in fluctuating environments

open access: yesFunctional Ecology, Volume 39, Issue 11, Page 3061-3082, November 2025.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Increasing attention is being devoted to the study of phenotypic plasticity in social environments. However, much remains unknown about the selection pressures driving the evolution of social plasticity, as well as the pathways by which social plasticity may facilitate ...
Jordan S. Martin   +4 more
wiley   +1 more source

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

open access: yesCell Reports, 2018
Summary: Precision oncology uses genomic evidence to match patients with treatment but often fails to identify all patients who may respond. The transcriptome of these “hidden responders” may reveal responsive molecular states. We describe and evaluate a
Gregory P. Way   +737 more
doaj   +1 more source

Reconstruction of deglacial sea surface temperatures in the tropical Pacific from selective analysis of a fossil coral [PDF]

open access: yes, 2005
The Sr/Ca of coral skeletons demonstrates potential as an indicator of sea surface temperatures (SSTs). However, the glacial-interglacial SST ranges predicted from Sr/Ca of fossil corals are usually higher than from other marine proxies.
Allison, N.   +5 more
core   +1 more source

Transgenerational plasticity research: Challenges and opportunities

open access: yesFunctional Ecology, Volume 39, Issue 11, Page 3083-3104, November 2025.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Transgenerational plasticity (TGP) is a type of non‐genetic inheritance whereby one generation's environment affects a subsequent generation's phenotype. It can influence the persistence of organisms in stressful climatic conditions through allowing rapid phenotypic ...
Caitlin McAndry   +3 more
wiley   +1 more source

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

open access: yesCell Reports, 2018
Summary: Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles in cancer. We inferred lncRNAs that dysregulate cancer pathways, oncogenes, and tumor suppressors (cancer genes) by ...
Hua-Sheng Chiu   +736 more
doaj   +1 more source

21-cm observations and warm dark matter models [PDF]

open access: yes, 2019
Observations of the redshifted 21-cm signal (in absorption or emission) allow us to peek into the epoch of "dark ages" and the onset of reionization. These data can provide a novel way to learn about the nature of dark matter, in particular about the ...
Boyarsky, Alexey   +4 more
core   +3 more sources

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

open access: yesCell Reports, 2018
Summary: Protein ubiquitination is a dynamic and reversible process of adding single ubiquitin molecules or various ubiquitin chains to target proteins. Here, using multidimensional omic data of 9,125 tumor samples across 33 cancer types from The Cancer ...
Zhongqi Ge   +740 more
doaj   +1 more source

W*-superrigidity for Bernoulli actions of property (T) groups [PDF]

open access: yes, 2011
We consider group measure space II$_1$ factors $M=L^{\infty}(X)\rtimes\Gamma$ arising from Bernoulli actions of ICC property (T) groups $\Gamma$ (more generally, of groups $\Gamma$ containing an infinite normal subgroup with relative property (T)) and ...
Ioana, Adrian
core   +3 more sources

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