Results 191 to 200 of about 2,931 (237)

Adult-Onset Still's Disease With Suspected Steroid Hypersensitivity: A Case Report. [PDF]

Cureus
Abdul Gafoor A, Khalid A, Karim T.
europepmc   +1 more source

Risk of Inflammatory Bowel Disease Following Hospital‐Treated Infections and Modulatory Role of Host Genetics to Support a Multi‐Hit Pathogenesis Model

Advanced Science, EarlyView.
Hospital‐treated infections are linked to increased risk of inflammatory bowel disease in a large prospective cohort. This risk differs by infection burden, time since infection, and host immune‐genetic susceptibility. The findings support a multi‐hit pathogenesis model in which severe infection and inherited susceptibility jointly shape inflammatory ...
Haiming Zhuang, Lintao Dan, Xin Xiang, Xixian Ruan, Shuai Yuan, Jialu Yao, Jiawei Geng, Jonas F. Ludvigsson, Tian Fu, Candida Abreu, Laurent Peyrin‐Biroulet, Xue Li, Yi Xiao, Fernando Magro, Xiaoyan Wang, Jing Sun, Jie Chen   +16 more
wiley   +1 more source

Simultaneous diagnosis of adult-onset Still's disease and lymphoma: A case report and systematic review of the literature. [PDF]

Clin Case Rep
Bayala YLT, Ouedraogo I, Mourfou HE, Son BA, Yameogo WN, Tinni IA, Zabsonré Tiendrébéogo WJS, Ouedraogo DD.   +7 more
europepmc   +1 more source

Deconstruction of Human Age‐Related Cataract Capsules Defines Aging

Advanced Science, EarlyView.
We generate a comprehensive atlas of age‐related cataracts (ARC) at a single‐cell resolution, encompassing three disease states—mild cataract group (Mild), severe cortical cataract group (Severe_C), and severe nuclear cataract group (Severe_N). We find that ARC involves seven distinct lens capsule cell types, with notable differences in cellular ...
Qiaomei Tang, Ziyang Tong, Chunmei Fan, Silong Chen, Jiarui Guo, Jianghua Hu, Ke Yao, Zi Yin, Xiao Chen, Yibo Yu   +9 more
wiley   +1 more source

Adult-Onset Still's Disease Presenting With Leukopenia and Pulmonary Infiltrates: A Mimicker of Infection and Malignancy. [PDF]

Cureus
Vaezi Z, Amini A.
europepmc   +1 more source

High‐Throughput Mechanical Rupture of Nuclear Envelope and the Intracellular Dynamics of Massive Wound Repair

Advanced Science, EarlyView.
A microfluidic device with monolithically integrated nanostructures enables high‐throughput wounding of the cell membrane and nuclear envelope. The spatial distribution of charged multivesicular body protein 4B (CHMP4B) within the cell is mapped before and after wounding, showing involvement in repair of both the cell membrane and nuclear envelope ...
Apresio K. Fajrial, Leyla Akh, Stephanie E. Schneider, Wei Tan, Corey P. Neu, Xiaoyun Ding   +5 more
wiley   +1 more source

Adult-Onset Still's Disease in a Patient with Macrophage Activation Syndrome and Pre-Disseminated Intravascular Coagulation: A Case Report and Literature Review. [PDF]

J Inflamm Res
Xu J, Yang J, Hu Y, Zhao Z, Cai H, Yao Q, Shang W.   +6 more
europepmc   +1 more source

A Phosphorylation‐Induced Micellization Switch in the Low‐Complexity Domain of TDP‐43

Advanced Science, EarlyView.
Phosphorylation of TAR DNA‐binding protein's 43 kDa (TDP‐43) low‐complexity domain by casein kinase 1 delta (CK1δ) acts as a molecular switch, redirecting its self‐assembly from macroscopic phase separation toward finite‐sized, spherical block‐copolymer micelles of ∼30 nm.
Rodrigo F. Dillenburg, Anastasia Lopatina, Hao Ruan, Tom Scheidt, Simone Mosna, Emre Pekbilir, Julia Bieber, Frank Schäfer‐Depoix, Katharina Landfester, Carla Schmidt, Martin M. Möckel, Svenja Morsbach, Friederike Schmid, Dorothee Dormann, Lukas Stelzl, Martin Girard, Edward A. Lemke   +16 more
wiley   +1 more source

Atypical Presentation of Adult-Onset Still's Disease with Predominant Hepatic Involvement and Monocytosis: A Case Report. [PDF]

Clin Med Insights Case Rep
Elmezayen ZW, Marzouk ZZ, Adi M.
europepmc   +1 more source

Experience‐Dependent Reorganization of Hippocampal CA3 Neuronal Ensembles Associates With Memory Generalization

Advanced Science, EarlyView.
Mice can transfer the learned rule of spatial working memory to guide similar but novel tasks. Hippocampal CA3 populational activity dynamically reorganize during memory generalization, shifting from task‐specific to generalized coding over testing days. Sparse yet redundant neural representations of CA3 enable rule transfer and cognitive map formation,
Da Song, Zilu Zhu, Yujun Deng, Yujie Song, Hui Li, Junjun Ni, Zhenzhen Quan, Yan Yan, Hong Qing   +8 more
wiley   +1 more source