Results 41 to 50 of about 4,345 (272)

Protocol for the Foot in Juvenile Idiopathic Arthritis trial (FiJIA): a randomised controlled trial of an integrated foot care programme for foot problems in JIA [PDF]

open access: yes, 2009
<b>Background</b>: Foot and ankle problems are a common but relatively neglected manifestation of juvenile idiopathic arthritis. Studies of medical and non-medical interventions have shown that clinical outcome measures can be improved ...
A Manca   +60 more
core   +4 more sources

Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

open access: yesBMC Medicine, 2012
Background Germinal center kinase-like kinase (GLK, also termed MAP4K3), a member of the MAP4K family, may regulate gene transcription, apoptosis and immune inflammation in response to extracellular signals.
Chen Der-Yuan   +6 more
doaj   +1 more source

Effects of HLA-DRB1 alleles on susceptibility and clinical manifestations in Japanese patients with adult onset Still’s disease [PDF]

open access: yes, 2017
BackgroundHLA-DRB1 alleles are major determinants of genetic predisposition to rheumatic diseases. We assessed whether DRB1 alleles are associated with susceptibility to particular clinical features of adult onset Still’s disease (AOSD) in a Japanese ...
Asano Tomoyuki   +29 more
core   +2 more sources

Pneumonitis in Adult Onset Still’s Disease: Uncommon or Under Diagnosed?

open access: yesActa Médica Portuguesa, 2017
The adult onset Still’s Disease is an uncommon entity characterized by multiple clinical manifestations. Pneumonitis, less often considered, deserves particular emphasis given the need for differential diagnosis and because it can progress to severe ...
Silvia Fernandes   +3 more
doaj   +1 more source

Interleukin-18 [PDF]

open access: yes, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
Gracie, J.A.   +2 more
core   +1 more source

ADULT-ONSET STILL'S DISEASE TODAY

open access: yesНаучно-практическая ревматология, 2017
The lecture gives an update on adult-onset Still's disease, including that on the specific features of the clinical picture and treatment of this disease.
Yu. V. Muravyev, V. V. Lebedeva
doaj   +1 more source

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis [PDF]

open access: yes, 2010
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (M. tuberculosis), is a major cause of morbidity and mortality worldwide and efforts to control TB are hampered by difficulties with diagnosis, prevention and treatment 1,2.
A Falk   +49 more
core   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd   +3 more
wiley   +1 more source

Association between adult-onset still’s disease and COVID-19: A report of two cases and brief review

open access: yesSAGE Open Medical Case Reports
Adult-onset still’s disease is a rare multisystemic autoinflammatory disorder with an estimated annual incidence of 0.16–0.62 per 100,000 individuals worldwide. It is typically considered a diagnosis of exclusion.
Sarah Fet-He   +2 more
doaj   +1 more source

Adult Onset Still's Disease - current state of knowledge

open access: yesJournal of Education, Health and Sport
Introduction: Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. AOSD lies at the crossroads of innate and adaptive immunity, highlighting the complexity of its pathogenesis.
Anna Centkowska   +9 more
doaj   +1 more source

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