Results 51 to 60 of about 118,654 (333)

Association Between Peripheral Eosinophilia and Clinical Characteristics of Adult-onset Still’s Disease with Persistent Eruption: A Retrospective Study

Acta Dermato-Venereologica, 2021
Persistent eruption occurs in a subset of patients with adult-onset Still’s disease. In our experience, a considerable proportion of these patients present with peripheral eosinophilia.
Jia-Wei Liu, Tian Chen, Wei Liu, Ru-Xuan Chen, Yue-Tong Qian, Yan Tan, Dong-Lai Ma   +6 more
doaj   +1 more source

Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis [PDF]

, 2011
Introduction There has been no report in the literature of a soluble form of interleukin (IL)-18 receptor α (IL-18Rα). In this study, we evaluated the levels and characteristics of soluble IL-18Rα (sIL-18Rα) in the sera of patients with ...
Satoko Takei, Tomoaki Hoshino, Kazuko Matsunaga, Yuki Sakazaki, Masanori Sawada, Hanako Oda, Shin-ichi Takenaka, Haruki Imaoka, Takashi Kinoshita, Seiyo Honda, Hiroaki Ida, Taka-aki Fukuda, Hisamichi Aizawa   +12 more
core   +1 more source

Disparities in the prevalence of clinical features between systemic juvenile idiopathic arthritis and adult-onset Still’s disease

Rheumatology, 2022
Objective To compare clinical features and treatments of patients with systemic JIA (sIJA) and adult-onset Still’s disease (AOSD). Methods The clinical charts of consecutive patients with sJIA by International League of Association of Rheumatology ...
P. Ruscitti, V. Natoli, A. Consolaro, R. Caorsi, S. Rosina, G. Giancane, Roberta Naddei, I. Di Cola, C. Di Muzio, O. Berardicurti, D. Iacono, I. Pantano, G. Rozza, S. Rossi, L. De Stefano, S. Balduzzi, A. Vitale, F. Caso, L. Costa, M. Prete, L. Navarini, A. Iagnocco, F. Atzeni, G. Guggino, F. Perosa, L. Cantarini, B. Frediani, C. Montecucco, F. Ciccia, P. Cipriani, M. Gattorno, R. Giacomelli, A. Ravelli   +32 more
semanticscholar   +1 more source

Fever and erythema: exclude all and then… think of Still’s disease!

Italian Journal of Medicine, 2016
Adult-onset Still’s disease is a rare disease. Diagnosis of Still’s disease is often difficult to achieve. Herein, we describe our diagnostic approach in a case report regarding an adult patient who presented with fever, erythema, lymphadenopathy and ...
Marta Maset, Elena Garlatti Costa, Giorgio Siro Carniello, Silvia Grazioli, Michela Ghersetti, Pietro Casarin   +5 more
doaj   +1 more source

Tofacitinib in refractory adult-onset Still’s disease: 14 cases from a single centre in China

Annals of the Rheumatic Diseases, 2020
Adult-onset Still’s disease (AOSD) is an autoinflammatory disease characterised by spiking fever, rash, polyarthralgia, sore throat and even life-threatening complications, such as macrophage activation syndrome and fulminant hepatitis.
Qiong-yi Hu, Mengyan Wang, Jinchao Jia, Jialin Teng, Huihui Chi, Tingting Liu, Honglei Liu, Xiaobing Cheng, Junna Ye, Yutong Su, Yue Sun, Zhuochao Zhou, Liyan Wan, Zhihong Wang, Fan Wang, Hui Shi, Chengde Yang   +16 more
semanticscholar   +1 more source

Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

BMC Medicine, 2012
Background Germinal center kinase-like kinase (GLK, also termed MAP4K3), a member of the MAP4K family, may regulate gene transcription, apoptosis and immune inflammation in response to extracellular signals.
Chen Der-Yuan, Chuang Huai-Chia, Lan Joung-Liang, Chen Yi-Ming, Hung Wei-Ting, Lai Kuo-Lung, Tan Tse-Hua   +6 more
doaj   +1 more source

Interleukin-18 [PDF]

, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
Gracie, J.A., McInnes, I.B., Robertson, S.E.   +2 more
core   +1 more source

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis [PDF]

, 2010
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (M. tuberculosis), is a major cause of morbidity and mortality worldwide and efforts to control TB are hampered by difficulties with diagnosis, prevention and treatment 1,2.
A Falk, AM Cooper, AM Cooper, Anne O’Garra, Asuncion Mejias, C Auffray, C Dye, C Manca, C Manca, C Telesca, CE Barry III, Charles Quinn, Christine M. Graham, D Chaussabel, D Ordway, D Salisbury, Damien Chaussabel, DB Young, Derek Blankenship, EB Eruslanov, EC Baechler, F Allantaz, Finlay W. McNab, Jacques Banchereau, Jason Skinner, JL Casanova, JL Flynn, John J. Cush, JS Beck, Katalin A. Wilkinson, L Bennett, M Jacobsen, Matthew P. R. Berry, MI Ardura, O Ramilo, Octavio Ramilo, Onn M. Kon, R Mistry, R Pankla, Ranju Dhawan, Robert J. Wilkinson, Romain Banchereau, SH Kaufmann, Susannah A. A. Bloch, SY Eum, T Decker, Tolu Oni, V Pascual, Virginia Pascual, Zhaohui Xu   +49 more
core   +1 more source

Is exogenous administration of IL-1ra (anakinra) likely to induce severe depression? [PDF]

, 2010
International ...
Aspe, Gilles, Autret-Leca, Elisabeth, Guilmot, Jean-Louis, Jonville-Bera, Annie-Pierre, Magnant, Julie   +4 more
core   +3 more sources

Enhanced type I interferon signature induces neutrophil extracellular traps enriched in mitochondrial DNA in adult-onset Still's disease.

Journal of Autoimmunity, 2022
Adult-onset Still's disease (AOSD) is a rare but clinically well-known auto-inflammatory disorder. Cytokine storm, the hallmark of AOSD, is mediated by neutrophil hyperactivation and enhanced neutrophil extracellular trap (NET) formation.
Yuning Ma, Mengyan Wang, Jinchao Jia, Jianfen Meng, Jialin Teng, Dehao Zhu, Hui Shi, Yue Sun, Yutong Su, Honglei Liu, Xiaobing Cheng, Junna Ye, Huihui Chi, Tingting Liu, Xia Chen, Liyan Wan, Zhuochao Zhou, Fan Wang, Dong‐Hong He, Chengde Yang, Qiong-yi Hu   +20 more
semanticscholar   +1 more source