Results 61 to 70 of about 118,654 (333)

Pneumonitis in Adult Onset Still’s Disease: Uncommon or Under Diagnosed?

Acta Médica Portuguesa, 2017
The adult onset Still’s Disease is an uncommon entity characterized by multiple clinical manifestations. Pneumonitis, less often considered, deserves particular emphasis given the need for differential diagnosis and because it can progress to severe ...
Silvia Fernandes, Margarida Almeida, José Alberto Pereira da Silva, José Carlos Romeu   +3 more
doaj   +1 more source

Effects of HLA-DRB1 alleles on susceptibility and clinical manifestations in Japanese patients with adult onset Still’s disease [PDF]

, 2017
BackgroundHLA-DRB1 alleles are major determinants of genetic predisposition to rheumatic diseases. We assessed whether DRB1 alleles are associated with susceptibility to particular clinical features of adult onset Still’s disease (AOSD) in a Japanese ...
Asano Tomoyuki, Eguchi Katsumi, Fujikawa Keita, Furukawa Hiroshi, Ito Tomoyuki, Iwanaga Nozomi, Izumi Yasumori, Kawakami Atsushi, Kobayashi Daisuke, Kobayashi Hiroko, Koga Tomohiro, Migita Kiyoshi, Nakamura Tadashi, Nonaka Fumiaki, Ohira Hiromasa, Sato Shuzo, Shimizu Toshimasa, Suzuki Eiji, Tohma Shigeto, Tsuchiya Naoyuki, Ubara Yoshifumi, Ueki Yukitaka, Umeda Masataka, Watanabe Hiroshi, Yamasaki Satoshi, Yashiro Makiko, Yasunami Michio, Yoshiura Koh-ichiro, 古川 宏, 土屋 尚之   +29 more
core   +2 more sources

Response to Interleukin-1 Inhibitors in 140 Italian Patients with Adult-Onset Still’s Disease: A Multicentre Retrospective Observational Study

Frontiers in Pharmacology, 2017
Background: Interleukin (IL)-1 plays a crucial role in the pathogenesis of Adult onset Still’s disease (AOSD). Objectives: To evaluate the efficacy and safety of anakinra (ANA) and canakinumab (CAN) in a large group of AOSD patients.
S. Colafrancesco, R. Priori, G. Valesini, L. Argolini, E. Baldissera, E. Bartoloni, D. Cammelli, G. Canestrari, L. Cantarini, E. Cavallaro, G. Cavalli, L. Cerrito, P. Cipriani, L. Dagna, G. D. Marchi, S. Vita, G. Emmi, G. Ferraccioli, M. Frassi, M. Galeazzi, R. Gerli, R. Giacomelli, E. Gremese, F. Iannone, G. Lapadula, G. Lopalco, R. Manna, A. Mathieu, C. Montecucco, M. Mosca, I. Piazza, M. Piga, I. Pontikaki, M. Romano, S. Rossi, M. Rossini, P. Ruscitti, E. Silvestri, C. Stagnaro, R. Talarico, A. Tincani, O. Viapiana, G. Vitiello, F. Fabris, S. Bindoli, L. Punzi, P. Galozzi, P. Sfriso   +47 more
semanticscholar   +1 more source

ADULT-ONSET STILL'S DISEASE TODAY

Научно-практическая ревматология, 2017
The lecture gives an update on adult-onset Still's disease, including that on the specific features of the clinical picture and treatment of this disease.
Yu. V. Muravyev, V. V. Lebedeva
doaj   +1 more source

Interleukin-18 Is a Potential Biomarker to Discriminate Active Adult-Onset Still’s Disease From COVID-19

Frontiers in Immunology, 2021
Background Hyperinflammation with dysregulated production of galectins and cytokines may develop in COVID-19 or adult-onset Still’s disease (AOSD). Given the similar clinical features in both diseases, it is necessary to identify biomarkers that can ...
Po‐Ku Chen, J. Lan, Po-Hao Huang, J. Hsu, Ching-Kun Chang, N. Tien, Hui-Ju Lin, Der-Yuan Chen   +7 more
semanticscholar   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Association between adult-onset still’s disease and COVID-19: A report of two cases and brief review

SAGE Open Medical Case Reports
Adult-onset still’s disease is a rare multisystemic autoinflammatory disorder with an estimated annual incidence of 0.16–0.62 per 100,000 individuals worldwide. It is typically considered a diagnosis of exclusion.
Sarah Fet-He, Gabriel Ibarra Lecompte, Alejandro José Quiroz Alfaro   +2 more
doaj   +1 more source

Adult Onset Still's Disease - current state of knowledge

Journal of Education, Health and Sport
Introduction: Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. AOSD lies at the crossroads of innate and adaptive immunity, highlighting the complexity of its pathogenesis.
Anna Centkowska, Natalia Katarzyna Wagner-Bieleń, Martyna Zwierzchowska, Agata Antoniak, Anna Maria Jocz, Joanna Karina Banaśkiewicz, Aleksandra Maria Żyta, Gabriela Helena Dąbrowska, Maria Anna Żmijewska, Jakub Ziółkowski   +9 more
doaj   +1 more source

Adult-onset Still’s disease in pregnancy: case report and literature review

Clinical and Experimental Obstetrics & Gynecology, 2021
Background: Adult-onset Still’s disease (AOSD) is a clinical syndrome whose etiology and pathogenesis remain unclear. The clinical symptoms of AOSD mainly include fever, erythema, arthralgia and muscle pain, which cannot be diagnosed by specific ...
Liang Chao, Li Jia, Ke-Fang Wang
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source