Results 81 to 90 of about 4,345 (272)

Adult-Onset Still's Disease: A Review

Proceedings of Singapore Healthcare, 2013
Adult-onset Still's disease (AOSD) is an uncommon inflammatory condition characterised by high fever, leukocytosis with neutrophilia, arthralgia and skin rash.
Weng Seng Fong MBBS (Singapore), MRCP (UK), Nai Lee Lui MBBS (Singapore), MRCP (UK) M.Med (Int. Med) Singapore   +1 more
doaj   +1 more source

Acute liver transplantation in a 41-year-old male patient presenting symptoms of adult-onset Still's disease [PDF]

, 2011
L
Andrès E., Bywaters E.G., Coffernils M., Cush J.J., Fautrel B., Ishikawa M., Kadar J., Linde B., Mehrpoor G., Mert A., Motoo Y., Nemes B., Nemes B., Nemes B., Ogata A., Singh S., Still G.F., Taccone F.S., Takami A., Teran A., Yamaguchi M., Zhu G.   +21 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Anakinra for the treatment of adult-onset Still's disease [PDF]

, 2018
: Introduction: Adult onset Still's disease (AOSD) is an uncommon systemic inflammatory disease on the clinical spectrum of autoinflammatory disorders.
Atienza Mateo, Belén, Castañeda Sanz, Santos, González-Gay Mantecón, Miguel Ángel, Martín Varillas, José Luis, Serra López-Matencio, José María   +4 more
core   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Macrophage Activation Syndrome Associated with Adult-Onset Still’s Disease Successfully Treated with Anakinra

Case Reports in Rheumatology, 2016
Macrophage activation syndrome (MAS) is a potentially fatal complication of Adult-Onset Still’s disease (Still’s disease). Whereas an increasing body of evidence supports interleukin-1 (IL-1) blockade as a promising treatment for Still’s disease, whether
Aswini Kumar, Hiroshi Kato
doaj   +1 more source

Tocilizumab for the treatment of adult-onset Still's disease [PDF]

, 2019
Adult-onset Still´s disease (AOSD) is a systemic inflammatory condition that affects mainly young people. The clinical course consists of two distinctive patterns: one with a predominance of systemic symptoms and another manifested by progressive chronic
Atienza Mateo, Belén, Castañeda, Santos, García-Castañeda, Noelia, González-Gay Mantecón, Miguel Ángel, Martín Varillas, José Luis, Martínez-Quintanilla, Dolores   +5 more
core   +2 more sources

Adult Onset Still's Disease

Faridpur Medical College Journal, 2017
Adult Still's disease is rare disease presented with high spiking fever, joint pain, rash, organomegaly and serositis. It is difficult to diagnose as it closely mimics with many systemic diseases, so it can be diagnosed after exclusion of them. There are lots of diagnostic criteria, of them Yamaguchi's criteria is well established.
MM Shahin Ul Islam, Mst Naznin Sarker, Md Iqbal Hossain, Mohammad Iqbal Hossain, Muhammad Kamruzzaman   +4 more
openaire   +2 more sources