Results 101 to 110 of about 7,604,512 (372)

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

"It Is Easy Using My Apps:" Understanding Technology Use and Needs of Adults with Down Syndrome [PDF]

open access: yes
Assistive technologies for adults with Down syndrome (DS) need designs tailored to their specific technology requirements. While prior research has explored technology design for individuals with intellectual disabilities, little is understood about the needs and expectations of adults with DS.
arxiv   +1 more source

1968-1970 Adult Basic Education - Mississippi Module [PDF]

open access: yes, 1968
1968 to 1970 Adult Basic Education teaching program Mississippi ...
Appalachian Adult Education Center
core   +1 more source

Was it worth it? A comparison of the role of adult education and training in the labour market insertion and progress of men and women in the West of Scotland: results of qualitative research [PDF]

open access: yes, 2000
Despite a number of relevant longitudinal studies carried out in Sweden, Finland, Norway and the United States of America, there is a relative paucity of research into the long-term outcomes of adult return to learning.
Clayton, P.
core   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

The Adult Learning Center [PDF]

open access: yes, 1972
A September of 1972 publication titled The Adult Learning Center distributed by the Appalachian Adult Education Center at Morehead State ...
Appalachian Adult Education Center
core   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Experiences, attitudes, and knowledge of medical students regarding intellectual and developmental disability: a Canadian study

open access: yesBMC Medical Education
Background As the healthcare of individuals with intellectual and developmental disabilities (IDD) shifts toward community-based services, physicians in all areas of medicine are more likely to care for this population.
Gabriel Tarzi   +9 more
doaj   +1 more source

Can early Burkholderia cepacia complex infection in cystic fibrosis be eradicated with antibiotic therapy?

open access: yesFrontiers in Cellular and Infection Microbiology, 2011
IntroductionOrganisms of the Burkholderia cepacia complex (BCC) are important pathogens in cystic fibrosis (CF). The majority of those who acquire BCC develop chronic infection but it can also result in rapid decline in a significant minority.
Alex eHorsley   +7 more
doaj   +1 more source

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