Results 131 to 140 of about 5,197,820 (319)

BSL L2: Story: First Day at school transcript

, 2013
BSL – British Sign Language LAL – Lancashire Adult Learning Level 2 Stories – First Day at school ...
Lancashire Adult Learning
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

BSL – L2 vocab: Education – Lessons

, 2013
BSL – British Sign Language LAL – Lancashire Adult Learning Vocabulary Level 2 Education ...
Lancashire Adult Learning
core  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Patient–ventilator synchrony under non-invasive ventilation is improved by an automated real time waveform analysis algorithm: a bench study

Intensive Care Medicine Experimental
Background Because of inherent leaks, obtaining good patient–ventilator synchrony during non-invasive ventilation (NIV) is challenging. The IntelliSync + ® software (Hamilton medical, Bonaduz, CH), that can be used together with the NIV mode, performs ...
Yann Renaud, Jocelyne Auroi, Davy Cabrio, Ermes Lupieri, Jean-Daniel Chiche, Lise Piquilloud   +5 more
doaj   +1 more source

BSL – L2 vocab: Education – Communication methods

, 2013
BSL – British Sign Language LAL – Lancashire Adult Learning Vocabulary Level 2 Education ...
Lancashire Adult Learning
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Aortic arch surgery in real-life practice: is the frozen elephant trunk always a better option than conventional aortic arch replacement?

Journal of Cardiothoracic Surgery
Objective Management of aortic arch disease (AAD) is complex due to its involvement in multiple aortic segments and the variety of patient presentations.
Maxime Zimmermann, Matteo Pozzi, Fadi Farhat, Marco Vola, Jean-François Obadia, Antoine Millon, Daniel Grinberg   +6 more
doaj   +1 more source

BSL – L2 vocab: Health– Treatments and Hospital

, 2013
BSL – British Sign Language LAL – Lancashire Adult Learning Vocabulary Level 2 Health– Treatments and ...
Lancashire Adult Learning
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source