Results 161 to 170 of about 11,441,017 (408)

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

ADULT GAUCHER’S DISEASE, WITH SPECIAL REFERENCE TO THE VARIATIONS IN ITS CLINICAL COURSE AND THE VALUE OF STERNAL PUNCTURE AS AN AID TO ITS DIAGNOSIS [PDF]

, 1948
J Groen, A. H. GARRER
openalex   +1 more source

Recommendations for Incorporating Postsecondary and Workforce Data into Statewide Longitudinal Data Systems [PDF]

, 2010
Outlines the need for data systems to assess educational transitions, completions, and labor market outcomes of adult students and workers in postsecondary, adult education, and skill development programs in order to strengthen policies and ...
Andrew Reamer, Brandon Roberts, Evelyn Ganzglass, Rachel Unruh, Whitney Smith   +4 more
core  

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

Cytological Identification of Proliferating Donor Cells in Chick Embryos injected with Adult Chicken Blood [PDF]

, 1959
P. M. Biggs, L. N. Payne
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Depression in adults.

Clinical evidence, 2006
[no abstract available]
Geddes J., Butler R., Hatcher S., CIPRIANI, Andrea, Price J., Carney S., Von Korff M.   +6 more
openaire   +3 more sources

Evaluating cloudcare, a population health management system, in persons with type 1 diabetes: an observational study

BMC Endocrine Disorders
Background Innovations in diabetes technology have consistently improved outcomes of persons with type1 diabetes (PWDs). However, the volumes of data that these technologies yield require different workflows to alleviate healthcare professionals’ (HCPs ...
Cornelis A. J. van Beers, Sander Last, Pim Dekker, Erwin Birnie, Nico Riegman, Francisca van der Pluijm, Christine Fransman, Henk J. Veeze, Henk-Jan Aanstoot   +8 more
doaj   +1 more source

The Measurement and Appraisal of Adult Intelligence

, 1958
A. Stanley Webster, David Wechsler
openalex   +2 more sources

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Science, 2010
F. Ginhoux, F. Ginhoux, M. Greter, M. Leboeuf, Sayan Nandi, Peter See, Solen Gokhan, M. Mehler, S. Conway, L. Ng, E. Stanley, I. Samokhvalov, M. Merad   +12 more
semanticscholar   +1 more source