Results 231 to 240 of about 5,197,820 (319)

Toxic and repellent effects of hemp leaf extracts and cannabidiol against adult female yellow fever mosquitoes, Aedes aegypti. [PDF]

PLoS One
Martínez Rodríguez EJ, Phelan PL, Canas L, Acosta N, Feliciano PN, Tubbs J, Loperena E, Rakotondraibe HL, Piermarini PM.   +8 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Correction to "Diagnosis, Treatment, and Prognosis of Adult Pancreatoblastoma". [PDF]

Cancer Med
europepmc   +1 more source

Effects of Age Category and eCG Dose on Reproductive Performance in Ile-de-France Ewe Lambs and Adult Ewes Under Seasonal-Transition Field Conditions. [PDF]

Vet Sci
Ciftci MF, Satilmis F.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Childhood ADHD and Its Adult Mimics: When First-Time ADHD Diagnoses in Adulthood May Reflect Other Conditions-A Narrative Review. [PDF]

Brain Sci
Cuomo A, Pinzi M, Fagiolini A.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

A Comparison of Juvenile and Adult Sunflower Sea Star Transcriptomic Responses to Challenge With Sea Star Wasting Disease Tissue Homogenates. [PDF]

Ecol Evol
Crandall G, Gehman AM, Davis K, Prentice MB, Harvell D, White SJ, Hershberger P, Roberts S.   +7 more
europepmc   +1 more source