Results 261 to 270 of about 3,877,802 (324)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Factors influencing mutual support among older people in China: a cross-sectional study. [PDF]

Front Public Health
Xu L, Lin L, Huang X, Guan A, Cheng L, Zheng Y, Zhang S.   +6 more
europepmc   +1 more source

A subset of cortical areas exhibit adult-like functional network patterns in early childhood. [PDF]

Dev Cogn Neurosci
Tu JC, Wang Y, Wang X, Dierker D, Sobolewski CM, Day TKM, Kardan O, Miranda-Domínguez Ó, Moore LA, Feczko E, Fair DA, Elison JT, Gordon EM, Laumann TO, Eggebrecht AT, Wheelock MD.   +15 more
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Older adult stroke survivors' needs and perspectives of a stroke app: a qualitative study. [PDF]

BMC Geriatr
Cao W, Li A, Kadir AA, Chen J, Chen L, Li Q, Hassan II.   +6 more
europepmc   +1 more source

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

FEBS Open Bio, EarlyView.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques, Edit Ábrahám, Hiromi Muramatsu, Daniel Youssef Bargieri, Norbert Pardi, Zoltán Lipinszki   +5 more
wiley   +1 more source

Sex-specific effects of early-life adversity on adult fitness in a wild mammal. [PDF]

Proc Biol Sci
Drake ED, Ravindran S, Bal X, Pemberton JM, Pilkington JG, Nussey DH, Froy H.   +6 more
europepmc   +1 more source

An Explanation of the Non-Production of Fertilized Eggs by Adult Male-Producing Females in a Species of Asplanchna

, 1913
D. D. Whitney
openalex   +2 more sources

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source