Results 51 to 60 of about 6,215,718 (273)

Expanding Services for Disadvantaged Adults in Rowan County [PDF]

open access: yes, 1975
A report titled Expanding Services for Disadvantaged Adults in Rowan County submitted by Appalachian Adult Education Center at Morehead State University in March of ...
Appalachian Adult Education Center
core   +1 more source

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

PEEP-FiO2 table versus EIT to titrate PEEP in mechanically ventilated patients with COVID-19-related ARDS

open access: yesCritical Care, 2022
Rationale It is unknown how to titrate positive end-expiratory pressure (PEEP) in patients with COVID-19-related acute respiratory distress syndrome (ARDS). Guidelines recommend the one-size-fits-all PEEP-FiO2 table.
Peter Somhorst   +3 more
doaj   +1 more source

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

Wearable cardioverter-defibrillator (life-vest): A feasible bridging treatment in adult congenital heart disease

open access: yesIndian Pacing and Electrophysiology Journal, 2022
Background: Wearable cardioverter-defibrillators (WCDs) are currently used in patients at temporarily heightened risk for sudden cardiac death (SCD) who are temporarily unable to receive an implantable cardioverter-defibrillator (ICD).
Berardo Sarubbi   +10 more
doaj  

Advanced HIV disease management practices within inpatient medicine units at a referral hospital in Zambia: a retrospective chart review

open access: yesAIDS Research and Therapy, 2022
Background Zambia recently achieved UNAIDS 90-90-90 treatment targets for HIV epidemic control; however, inpatient facilities continue to face a large burden of patients with advanced HIV disease and HIV-related mortality.
Nyuma Mbewe   +11 more
doaj   +1 more source

Continuing AAEC Institute Series for the Expansion of Public Library Services to Disadvantaged Adults in Kentucky: Proposal to the Kentucky Department of Library and Archives [PDF]

open access: yes, 1974
Proposal to the Kentucky Department of Library and Archives titled Continuing AAEC Institute Series for the Expansion of Public Library Services to Disadvantaged Adults in Kentucky written by the Appalachian Adult Education Center on August 29 ...
Appalachian Adult Education Center
core   +1 more source

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

open access: yesFEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka   +6 more
wiley   +1 more source

Effect of preoperative right ventricular dysfunction and dilatation on survival after left ventricular surgical restoration

open access: yesThe Cardiothoracic Surgeon
Background This study investigated the impact of preoperative right ventricular (RV) dysfunction and dilatation on survival outcomes following left ventricular surgical restoration (LVSR) in patients with ischemic cardiomyopathy. A retrospective analysis
Abdelhameed Elsayed   +7 more
doaj   +1 more source

Paraquat ingestion in an adult with cystic fibrosis (CF): Diagnostic and management dilemmas

open access: yesRespirology Case Reports, 2023
N,N'‐dimethyl‐4,4'bipyridinium dichloride (Paraquat) is a potent herbicide used widely in agriculture. We report the effects of an ingestion of paraquat by a 28 year old male with cystic fibrosis and the diagnostic and management challenges this posed in
Ieuan E. S. Evans   +8 more
doaj   +1 more source

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