Results 151 to 160 of about 1,533,383 (278)
Genomic and proteomic insights into hidradenitis suppurativa
A dual pathogenic model of HS involving both epithelial dysfunction and systemic inflammation is supported. The HLA‐DRA association hints at autoimmune overlap, but the proteomic signature which is dominated by innate immune mediators favours an autoinflammatory classification, which may guide future therapeutic strategies and patient stratification ...
Maria Argyropoulou +8 more
wiley +1 more source
Cumulative isotretinoin dosing, treatment response and acne relapse: A randomized controlled trial
In this randomized controlled trial, cumulative isotretinoin doses of 120 and 150 mg/kg showed similar relapse rates at 12 months. Both regimens achieved substantial and comparable reductions in inflammatory acne lesions across the face, chest and back.
Ruggero Cascio Ingurgio +16 more
wiley +1 more source
Evaluation of Point-of-Care Decision Support for Adult Acne Treatment by Primary Care Clinicians.
Li DG +5 more
europepmc +1 more source
Lactase Persistence, Milk Intake, and Adult Acne: A Mendelian Randomization Study of 20,416 Danish Adults. [PDF]
Juhl CR +5 more
europepmc +1 more source
The worldwide burden of skin diseases: Lessons from the Global Burden of Disease data
Skin diseases are a major public health concern worldwide, causing significant personal, economic and social burdens. The Global Burden of Disease (GBD) initiative provides valuable insights but underestimates the burden of skin diseases, emphasizing the urgent need for improved data collection and global collaboration among stakeholders.
Luigi Naldi +16 more
wiley +1 more source
This systematic review included 38 studies assessing substance‐related and behavioural addictions in patients with chronic inflammatory skin diseases. Nicotine and alcohol use were the most frequently reported addictive behaviours. Addictions were associated with increased disease severity, impaired treatment outcomes and greater psychosocial burden ...
Enya Müller +5 more
wiley +1 more source
Dermatological Disease at a Tertiary Military Hospital in Burundi: A Retrospective Review
International Journal of Dermatology, EarlyView.
Doriane Sabushimike +5 more
wiley +1 more source
Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern +14 more
wiley +1 more source
In adults with moderate AD post‐TCS and ‐TCI, who may otherwise be eligible for systemic therapy, 1.5% ruxolitinib cream improved clinical signs and symptoms in the TRuE‐AD4 study. Abstract Background In patients with moderate atopic dermatitis (AD), topical corticosteroids (TCS) and topical calcineurin inhibitors (TCI) often do not sufficiently ...
José Manuel Carrascosa +14 more
wiley +1 more source

